000 02022 a2200577 4500
005 20250516043046.0
264 0 _c20110920
008 201109s 0 0 eng d
022 _a1546-170X
024 7 _a10.1038/nm.2370
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aRussell, Ryan C
245 0 0 _aLoss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia.
_h[electronic resource]
260 _bNature medicine
_cJun 2011
300 _a845-53 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
650 0 4 _aAnimals
650 0 4 _aDisease Models, Animal
650 0 4 _aHumans
650 0 4 _aJanus Kinase 2
_xantagonists & inhibitors
650 0 4 _aMice
650 0 4 _aMutation
_xgenetics
650 0 4 _aPolycythemia
_xetiology
650 0 4 _aProtein Multimerization
_xgenetics
650 0 4 _aPyrimidines
_xpharmacology
650 0 4 _aSulfonamides
_xpharmacology
650 0 4 _aSuppressor of Cytokine Signaling 1 Protein
650 0 4 _aSuppressor of Cytokine Signaling Proteins
_xgenetics
650 0 4 _aUbiquitin-Protein Ligases
_xgenetics
650 0 4 _aVon Hippel-Lindau Tumor Suppressor Protein
_xgenetics
700 1 _aSufan, Roxana I
700 1 _aZhou, Bing
700 1 _aHeir, Pardeep
700 1 _aBunda, Severa
700 1 _aSybingco, Stephanie S
700 1 _aGreer, Samantha N
700 1 _aRoche, Olga
700 1 _aHeathcote, Samuel A
700 1 _aChow, Vinca W K
700 1 _aBoba, Lukasz M
700 1 _aRichmond, Terri D
700 1 _aHickey, Michele M
700 1 _aBarber, Dwayne L
700 1 _aCheresh, David A
700 1 _aSimon, M Celeste
700 1 _aIrwin, Meredith S
700 1 _aKim, William Y
700 1 _aOhh, Michael
773 0 _tNature medicine
_gvol. 17
_gno. 7
_gp. 845-53
856 4 0 _uhttps://doi.org/10.1038/nm.2370
_zAvailable from publisher's website
999 _c20940315
_d20940315