| 000 | 01452 a2200409 4500 | ||
|---|---|---|---|
| 005 | 20250516041526.0 | ||
| 264 | 0 | _c20110621 | |
| 008 | 201106s 0 0 eng d | ||
| 022 | _a1095-9203 | ||
| 024 | 7 |
_a10.1126/science.1203799 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aChou, Hsin-Hung | |
| 245 | 0 | 0 |
_aDiminishing returns epistasis among beneficial mutations decelerates adaptation. _h[electronic resource] |
| 260 |
_bScience (New York, N.Y.) _cJun 2011 |
||
| 300 |
_a1190-2 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. | ||
| 650 | 0 | 4 | _aAdaptation, Physiological |
| 650 | 0 | 4 | _aAlleles |
| 650 | 0 | 4 | _aBiological Evolution |
| 650 | 0 | 4 | _aEpistasis, Genetic |
| 650 | 0 | 4 | _aEvolution, Molecular |
| 650 | 0 | 4 | _aGenes, Bacterial |
| 650 | 0 | 4 | _aGenetic Fitness |
| 650 | 0 | 4 | _aGenome, Bacterial |
| 650 | 0 | 4 |
_aGlutathione _xmetabolism |
| 650 | 0 | 4 |
_aMetabolic Networks and Pathways _xgenetics |
| 650 | 0 | 4 |
_aMethylobacterium extorquens _xcytology |
| 650 | 0 | 4 | _aModels, Genetic |
| 650 | 0 | 4 | _aMutation |
| 650 | 0 | 4 | _aSelection, Genetic |
| 700 | 1 | _aChiu, Hsuan-Chao | |
| 700 | 1 | _aDelaney, Nigel F | |
| 700 | 1 | _aSegrè, Daniel | |
| 700 | 1 | _aMarx, Christopher J | |
| 773 | 0 |
_tScience (New York, N.Y.) _gvol. 332 _gno. 6034 _gp. 1190-2 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1126/science.1203799 _zAvailable from publisher's website |
| 999 |
_c20895245 _d20895245 |
||