| 000 | 02488 a2200769 4500 | ||
|---|---|---|---|
| 005 | 20250516041453.0 | ||
| 264 | 0 | _c20110923 | |
| 008 | 201109s 0 0 eng d | ||
| 022 | _a1520-4804 | ||
| 024 | 7 |
_a10.1021/jm2003552 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aWang, Haishan | |
| 245 | 0 | 0 |
_aDiscovery of (2E)-3-{2-butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl}-N-hydroxyacrylamide (SB939), an orally active histone deacetylase inhibitor with a superior preclinical profile. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _cJul 2011 |
||
| 300 |
_a4694-720 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aAdministration, Oral |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aAntineoplastic Agents _xchemical synthesis |
| 650 | 0 | 4 |
_aBenzimidazoles _xchemical synthesis |
| 650 | 0 | 4 | _aBiological Availability |
| 650 | 0 | 4 | _aCell Line, Tumor |
| 650 | 0 | 4 | _aDogs |
| 650 | 0 | 4 | _aDrug Screening Assays, Antitumor |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 |
_aHistone Deacetylase 1 _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aHistone Deacetylase Inhibitors _xchemical synthesis |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aIsoenzymes _xantagonists & inhibitors |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 | _aMice, Inbred BALB C |
| 650 | 0 | 4 | _aMice, Nude |
| 650 | 0 | 4 |
_aMicrosomes, Liver _xmetabolism |
| 650 | 0 | 4 | _aNeoplasm Transplantation |
| 650 | 0 | 4 | _aQuantitative Structure-Activity Relationship |
| 650 | 0 | 4 | _aRats |
| 650 | 0 | 4 | _aRats, Wistar |
| 650 | 0 | 4 | _aStereoisomerism |
| 700 | 1 | _aYu, Niefang | |
| 700 | 1 | _aChen, Dizhong | |
| 700 | 1 | _aLee, Ken Chi Lik | |
| 700 | 1 | _aLye, Pek Ling | |
| 700 | 1 | _aChang, Joyce Wei Wei | |
| 700 | 1 | _aDeng, Weiping | |
| 700 | 1 | _aNg, Melvin Chi Yeh | |
| 700 | 1 | _aLu, Ting | |
| 700 | 1 | _aKhoo, Mui Ling | |
| 700 | 1 | _aPoulsen, Anders | |
| 700 | 1 | _aSangthongpitag, Kanda | |
| 700 | 1 | _aWu, Xiaofeng | |
| 700 | 1 | _aHu, Changyong | |
| 700 | 1 | _aGoh, Kee Chuan | |
| 700 | 1 | _aWang, Xukun | |
| 700 | 1 | _aFang, Lijuan | |
| 700 | 1 | _aGoh, Kay Lin | |
| 700 | 1 | _aKhng, Hwee Hoon | |
| 700 | 1 | _aGoh, Siok Kun | |
| 700 | 1 | _aYeo, Pauline | |
| 700 | 1 | _aLiu, Xin | |
| 700 | 1 | _aBonday, Zahid | |
| 700 | 1 | _aWood, Jeanette M | |
| 700 | 1 | _aDymock, Brian W | |
| 700 | 1 | _aKantharaj, Ethirajulu | |
| 700 | 1 | _aSun, Eric T | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 54 _gno. 13 _gp. 4694-720 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm2003552 _zAvailable from publisher's website |
| 999 |
_c20893638 _d20893638 |
||