| 000 | 01608 a2200385 4500 | ||
|---|---|---|---|
| 005 | 20250516040821.0 | ||
| 264 | 0 | _c20120117 | |
| 008 | 201201s 0 0 eng d | ||
| 022 | _a1875-8908 | ||
| 024 | 7 |
_a10.3233/JAD-2011-110101 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aHook, Gregory | |
| 245 | 0 | 0 |
_aThe cysteine protease inhibitor, E64d, reduces brain amyloid-β and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B, but not BACE1, β-secretase activity. _h[electronic resource] |
| 260 |
_bJournal of Alzheimer's disease : JAD _c2011 |
||
| 300 |
_a387-408 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 |
_aAlzheimer Disease _xdrug therapy |
| 650 | 0 | 4 |
_aAmyloid Precursor Protein Secretases _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aAmyloid beta-Peptides _xmetabolism |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aAspartic Acid Endopeptidases _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aBrain _xdrug effects |
| 650 | 0 | 4 |
_aCathepsin B _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aCysteine Proteinase Inhibitors _xpharmacology |
| 650 | 0 | 4 | _aDisease Models, Animal |
| 650 | 0 | 4 | _aGuinea Pigs |
| 650 | 0 | 4 |
_aLeucine _xanalogs & derivatives |
| 650 | 0 | 4 |
_aMemory _xdrug effects |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 | _aMice, Transgenic |
| 700 | 1 | _aHook, Vivian | |
| 700 | 1 | _aKindy, Mark | |
| 773 | 0 |
_tJournal of Alzheimer's disease : JAD _gvol. 26 _gno. 2 _gp. 387-408 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.3233/JAD-2011-110101 _zAvailable from publisher's website |
| 999 |
_c20874542 _d20874542 |
||