000			01996 a2200577 4500
005			20250516034703.0
264		0	_c20111209
008			201112s 0 0 eng d
022			_a1521-009X
024	7		_a10.1124/dmd.110.037234 _2doi
040			_aNLM _beng _cNLM
100	1		_aBungay, Peter J
245	0	0	_aPreclinical and clinical pharmacokinetics of PF-02413873, a nonsteroidal progesterone receptor antagonist. _h[electronic resource]
260			_bDrug metabolism and disposition: the biological fate of chemicals _cAug 2011
300			_a1396-405 p. _bdigital
500			_aPublication Type: Journal Article; Randomized Controlled Trial
650	0	4	_aAnimals
650	0	4	_aBiotransformation
650	0	4	_aCaco-2 Cells
650	0	4	_aChromatography, High Pressure Liquid
650	0	4	_aDogs
650	0	4	_aDose-Response Relationship, Drug
650	0	4	_aDouble-Blind Method
650	0	4	_aDrug Evaluation, Preclinical
650	0	4	_aHepatocytes _xenzymology
650	0	4	_aHumans
650	0	4	_aInjections, Intravenous
650	0	4	_aIntestinal Secretions _xchemistry
650	0	4	_aMale
650	0	4	_aMicrosomes, Liver _xenzymology
650	0	4	_aModels, Biological
650	0	4	_aMolecular Structure
650	0	4	_aPredictive Value of Tests
650	0	4	_aProspective Studies
650	0	4	_aProtein Binding
650	0	4	_aPyrazoles _xblood
650	0	4	_aRats
650	0	4	_aRats, Sprague-Dawley
650	0	4	_aReceptors, Progesterone _xantagonists & inhibitors
650	0	4	_aSolubility
650	0	4	_aSpecies Specificity
650	0	4	_aSulfones _xblood
650	0	4	_aTandem Mass Spectrometry
700	1		_aTweedy, Sarah
700	1		_aHowe, David C
700	1		_aGibson, Karl R
700	1		_aJones, Hannah M
700	1		_aMount, Natalie M
773	0		_tDrug metabolism and disposition: the biological fate of chemicals _gvol. 39 _gno. 8 _gp. 1396-405
856	4	0	_uhttps://doi.org/10.1124/dmd.110.037234 _zAvailable from publisher's website
999			_c20807358 _d20807358