000 01484 a2200385 4500
005 20250516033548.0
264 0 _c20111205
008 201112s 0 0 eng d
022 _a1096-0929
024 7 _a10.1093/toxsci/kfr083
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aWakefield, Ian
245 0 0 _aThe use of surrogate antibodies to evaluate the developmental and reproductive toxicity potential of an anti-TNFalpha PEGylated Fab' monoclonal antibody.
_h[electronic resource]
260 _bToxicological sciences : an official journal of the Society of Toxicology
_cJul 2011
300 _a170-6 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntibodies, Monoclonal, Humanized
_xtoxicity
650 0 4 _aCertolizumab Pegol
650 0 4 _aFemale
650 0 4 _aImmunoglobulin Fab Fragments
_xtoxicity
650 0 4 _aImmunoglobulin G
_xtoxicity
650 0 4 _aMale
650 0 4 _aPolyethylene Glycols
_xtoxicity
650 0 4 _aPregnancy
650 0 4 _aRats
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aTumor Necrosis Factor-alpha
_xmetabolism
700 1 _aStephens, Sue
700 1 _aFoulkes, Roly
700 1 _aNesbitt, Andrew
700 1 _aBourne, Tim
773 0 _tToxicological sciences : an official journal of the Society of Toxicology
_gvol. 122
_gno. 1
_gp. 170-6
856 4 0 _uhttps://doi.org/10.1093/toxsci/kfr083
_zAvailable from publisher's website
999 _c20773481
_d20773481