000 01895 a2200565 4500
005 20250516032258.0
264 0 _c20110715
008 201107s 0 0 eng d
022 _a1538-7445
024 7 _a10.1158/0008-5472.CAN-10-3482
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aGuo, Jianhui
245 0 0 _aFrequent truncating mutation of TFAM induces mitochondrial DNA depletion and apoptotic resistance in microsatellite-unstable colorectal cancer.
_h[electronic resource]
260 _bCancer research
_cApr 2011
300 _a2978-87 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aBase Sequence
650 0 4 _aCell Line, Tumor
650 0 4 _aCisplatin
_xpharmacology
650 0 4 _aColorectal Neoplasms
_xdrug therapy
650 0 4 _aCytochromes b
_xgenetics
650 0 4 _aDNA, Mitochondrial
_xgenetics
650 0 4 _aDNA-Binding Proteins
_xgenetics
650 0 4 _aDown-Regulation
650 0 4 _aFrameshift Mutation
650 0 4 _aHCT116 Cells
650 0 4 _aHumans
650 0 4 _aMice
650 0 4 _aMice, Nude
650 0 4 _aMicrosatellite Instability
650 0 4 _aMitochondrial Proteins
_xgenetics
650 0 4 _aTranscription Factors
_xgenetics
650 0 4 _aTranscription, Genetic
650 0 4 _aTransplantation, Heterologous
700 1 _aZheng, Li
700 1 _aLiu, Wenyong
700 1 _aWang, Xianshu
700 1 _aWang, Zemin
700 1 _aWang, Zehua
700 1 _aFrench, Amy J
700 1 _aKang, Dongchon
700 1 _aChen, Lin
700 1 _aThibodeau, Stephen N
700 1 _aLiu, Wanguo
773 0 _tCancer research
_gvol. 71
_gno. 8
_gp. 2978-87
856 4 0 _uhttps://doi.org/10.1158/0008-5472.CAN-10-3482
_zAvailable from publisher's website
999 _c20734979
_d20734979