| 000 | 01754 a2200505 4500 | ||
|---|---|---|---|
| 005 | 20250516031532.0 | ||
| 264 | 0 | _c20110704 | |
| 008 | 201107s 0 0 eng d | ||
| 022 | _a1520-4804 | ||
| 024 | 7 |
_a10.1021/jm1012819 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aRadi, Marco | |
| 245 | 0 | 0 |
_aDesign, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _cApr 2011 |
||
| 300 |
_a2610-26 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 |
_aAntineoplastic Agents _xchemical synthesis |
| 650 | 0 | 4 | _aCell Hypoxia |
| 650 | 0 | 4 | _aCell Line, Tumor |
| 650 | 0 | 4 | _aDrug Screening Assays, Antitumor |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aLeukemia _xpathology |
| 650 | 0 | 4 | _aMagnetic Resonance Spectroscopy |
| 650 | 0 | 4 | _aMass Spectrometry |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 |
_aPyrazoles _xchemical synthesis |
| 650 | 0 | 4 |
_aPyrimidines _xchemical synthesis |
| 700 | 1 | _aDreassi, Elena | |
| 700 | 1 | _aBrullo, Chiara | |
| 700 | 1 | _aCrespan, Emmanuele | |
| 700 | 1 | _aTintori, Cristina | |
| 700 | 1 | _aBernardo, Vincenzo | |
| 700 | 1 | _aValoti, Massimo | |
| 700 | 1 | _aZamperini, Claudio | |
| 700 | 1 | _aDaigl, Henry | |
| 700 | 1 | _aMusumeci, Francesca | |
| 700 | 1 | _aCarraro, Fabio | |
| 700 | 1 | _aNaldini, Antonella | |
| 700 | 1 | _aFilippi, Irene | |
| 700 | 1 | _aMaga, Giovanni | |
| 700 | 1 | _aSchenone, Silvia | |
| 700 | 1 | _aBotta, Maurizio | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 54 _gno. 8 _gp. 2610-26 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm1012819 _zAvailable from publisher's website |
| 999 |
_c20712602 _d20712602 |
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