000			01980 a2200553 4500
005			20250516031325.0
264		0	_c20110701
008			201107s 0 0 eng d
022			_a1091-6490
024	7		_a10.1073/pnas.1101143108 _2doi
040			_aNLM _beng _cNLM
100	1		_aHoffmann, Hans-Heinrich
245	0	0	_aBroad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis. _h[electronic resource]
260			_bProceedings of the National Academy of Sciences of the United States of America _cApr 2011
300			_a5777-82 p. _bdigital
500			_aPublication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650	0	4	_aAnimals
650	0	4	_aAntiviral Agents _xpharmacology
650	0	4	_aAutoradiography
650	0	4	_aCarbamates
650	0	4	_aCell Line, Tumor
650	0	4	_aCell Survival _xdrug effects
650	0	4	_aChickens
650	0	4	_aDNA Primers _xgenetics
650	0	4	_aDihydroorotate Dehydrogenase
650	0	4	_aFurans
650	0	4	_aHumans
650	0	4	_aIndoles _xpharmacology
650	0	4	_aLamivudine
650	0	4	_aMammals
650	0	4	_aNevirapine
650	0	4	_aOxadiazoles _xpharmacology
650	0	4	_aOxidoreductases Acting on CH-CH Group Donors _xmetabolism
650	0	4	_aPyrimidines _xbiosynthesis
650	0	4	_aPyrrolidinones
650	0	4	_aRaltegravir Potassium
650	0	4	_aSpecies Specificity
650	0	4	_aSulfonamides
650	0	4	_aTime Factors
650	0	4	_aVirus Replication _xdrug effects
650	0	4	_aViruses _xdrug effects
650	0	4	_abeta-Galactosidase _xmetabolism
700	1		_aKunz, Andrea
700	1		_aSimon, Viviana A
700	1		_aPalese, Peter
700	1		_aShaw, Megan L
773	0		_tProceedings of the National Academy of Sciences of the United States of America _gvol. 108 _gno. 14 _gp. 5777-82
856	4	0	_uhttps://doi.org/10.1073/pnas.1101143108 _zAvailable from publisher's website
999			_c20705705 _d20705705