000 02125 a2200565 4500
005 20250516025657.0
264 0 _c20110816
008 201108s 0 0 eng d
022 _a1527-7755
024 7 _a10.1200/JCO.2010.33.2312
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aWagle, Nikhil
245 0 0 _aDissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling.
_h[electronic resource]
260 _bJournal of clinical oncology : official journal of the American Society of Clinical Oncology
_cAug 2011
300 _a3085-96 p.
_bdigital
500 _aPublication Type: Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAdult
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aDNA Mutational Analysis
650 0 4 _aDisease Progression
650 0 4 _aDrug Resistance, Neoplasm
_xgenetics
650 0 4 _aFatal Outcome
650 0 4 _aGene Expression Profiling
650 0 4 _aHumans
650 0 4 _aIndoles
_xpharmacology
650 0 4 _aMAP Kinase Kinase 1
_xgenetics
650 0 4 _aMale
650 0 4 _aMelanoma
_xdrug therapy
650 0 4 _aMutation
650 0 4 _aPhosphatidylethanolamine Binding Protein
_xgenetics
650 0 4 _aPrecision Medicine
_xmethods
650 0 4 _aProtein Kinase Inhibitors
_xpharmacology
650 0 4 _aProto-Oncogene Proteins B-raf
_xgenetics
650 0 4 _aSkin Neoplasms
_xdrug therapy
650 0 4 _aSulfonamides
_xpharmacology
650 0 4 _aVemurafenib
700 1 _aEmery, Caroline
700 1 _aBerger, Michael F
700 1 _aDavis, Matthew J
700 1 _aSawyer, Allison
700 1 _aPochanard, Panisa
700 1 _aKehoe, Sarah M
700 1 _aJohannessen, Cory M
700 1 _aMacconaill, Laura E
700 1 _aHahn, William C
700 1 _aMeyerson, Matthew
700 1 _aGarraway, Levi A
773 0 _tJournal of clinical oncology : official journal of the American Society of Clinical Oncology
_gvol. 29
_gno. 22
_gp. 3085-96
856 4 0 _uhttps://doi.org/10.1200/JCO.2010.33.2312
_zAvailable from publisher's website
999 _c20655836
_d20655836