| 000 | 01903 a2200541 4500 | ||
|---|---|---|---|
| 005 | 20250516025628.0 | ||
| 264 | 0 | _c20110606 | |
| 008 | 201106s 0 0 eng d | ||
| 022 | _a1520-4804 | ||
| 024 | 7 |
_a10.1021/jm1013874 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aProcopiou, Panayiotis A | |
| 245 | 0 | 0 |
_aThe discovery of phthalazinone-based human H1 and H3 single-ligand antagonists suitable for intranasal administration for the treatment of allergic rhinitis. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _cApr 2011 |
||
| 300 |
_a2183-95 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aAdministration, Intranasal |
| 650 | 0 | 4 | _aAdministration, Oral |
| 650 | 0 | 4 |
_aDrug Discovery _xmethods |
| 650 | 0 | 4 |
_aHistamine H1 Antagonists _xadministration & dosage |
| 650 | 0 | 4 |
_aHistamine H3 Antagonists _xadministration & dosage |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 |
_aPhthalazines _xadministration & dosage |
| 650 | 0 | 4 | _aProtein Conformation |
| 650 | 0 | 4 |
_aReceptors, Histamine H1 _xchemistry |
| 650 | 0 | 4 |
_aReceptors, Histamine H3 _xmetabolism |
| 650 | 0 | 4 |
_aRhinitis _xdrug therapy |
| 700 | 1 | _aBrowning, Christopher | |
| 700 | 1 | _aBuckley, Jennifer M | |
| 700 | 1 | _aClark, Kenneth L | |
| 700 | 1 | _aFechner, Lise | |
| 700 | 1 | _aGore, Paul M | |
| 700 | 1 | _aHancock, Ashley P | |
| 700 | 1 | _aHodgson, Simon T | |
| 700 | 1 | _aHolmes, Duncan S | |
| 700 | 1 | _aKranz, Michael | |
| 700 | 1 | _aLooker, Brian E | |
| 700 | 1 | _aMorriss, Karen M L | |
| 700 | 1 | _aParton, Daniel L | |
| 700 | 1 | _aRussell, Linda J | |
| 700 | 1 | _aSlack, Robert J | |
| 700 | 1 | _aSollis, Steven L | |
| 700 | 1 | _aVile, Sadie | |
| 700 | 1 | _aWatts, Clarissa J | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 54 _gno. 7 _gp. 2183-95 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm1013874 _zAvailable from publisher's website |
| 999 |
_c20654380 _d20654380 |
||