000 01944 a2200529 4500
005 20250516025325.0
264 0 _c20110606
008 201106s 0 0 eng d
022 _a1873-2968
024 7 _a10.1016/j.bcp.2011.02.014
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aTrzeciakiewicz, Anna
245 0 0 _aIntramolecular cyclization of N-phenyl N'(2-chloroethyl)ureas leads to active N-phenyl-4,5-dihydrooxazol-2-amines alkylating β-tubulin Glu198 and prohibitin Asp40.
_h[electronic resource]
260 _bBiochemical pharmacology
_cMay 2011
300 _a1116-23 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAlkylating Agents
_xpharmacology
650 0 4 _aAmines
_xchemistry
650 0 4 _aAnimals
650 0 4 _aAspartic Acid
_xmetabolism
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aChromatography, High Pressure Liquid
650 0 4 _aCyclization
650 0 4 _aElectrophoresis, Gel, Two-Dimensional
650 0 4 _aFluorescent Antibody Technique
650 0 4 _aGlutamic Acid
_xmetabolism
650 0 4 _aMelanoma, Experimental
_xpathology
650 0 4 _aMice
650 0 4 _aProhibitins
650 0 4 _aRepressor Proteins
_xchemistry
650 0 4 _aSpectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
650 0 4 _aTubulin
_xchemistry
650 0 4 _aUrea
_xchemistry
700 1 _aFortin, Sébastien
700 1 _aMoreau, Emmanuel
700 1 _aC-Gaudreault, René
700 1 _aLacroix, Jacques
700 1 _aChambon, Christophe
700 1 _aCommunal, Yves
700 1 _aChezal, Jean-Michel
700 1 _aMiot-Noirault, Elisabeth
700 1 _aBouchon, Bernadette
700 1 _aDegoul, Françoise
773 0 _tBiochemical pharmacology
_gvol. 81
_gno. 9
_gp. 1116-23
856 4 0 _uhttps://doi.org/10.1016/j.bcp.2011.02.014
_zAvailable from publisher's website
999 _c20644363
_d20644363