000			02209 a2200601 4500
005			20250516025024.0
264		0	_c20110617
008			201106s 0 0 eng d
022			_a1520-4804
024	7		_a10.1021/jm101445p _2doi
040			_aNLM _beng _cNLM
100	1		_aHonda, Tadashi
245	0	0	_aTricyclic compounds containing nonenolizable cyano enones. A novel class of highly potent anti-inflammatory and cytoprotective agents. _h[electronic resource]
260			_bJournal of medicinal chemistry _cMar 2011
300			_a1762-78 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650	0	4	_aAflatoxin B1
650	0	4	_aAnimals
650	0	4	_aAnti-Inflammatory Agents, Non-Steroidal _xchemical synthesis
650	0	4	_aAntineoplastic Agents _xchemical synthesis
650	0	4	_aCells, Cultured
650	0	4	_aCytoprotection
650	0	4	_aEnzyme Induction
650	0	4	_aHeme Oxygenase-1 _xbiosynthesis
650	0	4	_aInterferon-gamma _xpharmacology
650	0	4	_aLiver _xdrug effects
650	0	4	_aLiver Neoplasms, Experimental _xchemically induced
650	0	4	_aMacrophages _xdrug effects
650	0	4	_aMale
650	0	4	_aMice
650	0	4	_aNAD(P)H Dehydrogenase (Quinone) _xbiosynthesis
650	0	4	_aNitric Oxide Synthase Type II _xantagonists & inhibitors
650	0	4	_aNitriles _xchemical synthesis
650	0	4	_aPentacyclic Triterpenes _xchemistry
650	0	4	_aPhenanthrenes _xchemical synthesis
650	0	4	_aPrecancerous Conditions _xchemically induced
650	0	4	_aRats
650	0	4	_aStereoisomerism
650	0	4	_aStomach _xdrug effects
650	0	4	_aStructure-Activity Relationship
700	1		_aYoshizawa, Hidenori
700	1		_aSundararajan, Chitra
700	1		_aDavid, Emilie
700	1		_aLajoie, Marc J
700	1		_aFavaloro, Frank G
700	1		_aJanosik, Tomasz
700	1		_aSu, Xiaobo
700	1		_aHonda, Yukiko
700	1		_aRoebuck, Bill D
700	1		_aGribble, Gordon W
773	0		_tJournal of medicinal chemistry _gvol. 54 _gno. 6 _gp. 1762-78
856	4	0	_uhttps://doi.org/10.1021/jm101445p _zAvailable from publisher's website
999			_c20636088 _d20636088