000 01993 a2200601 4500
005 20250516024705.0
264 0 _c20110705
008 201107s 0 0 eng d
022 _a1464-3405
024 7 _a10.1016/j.bmcl.2011.01.129
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aWatson, Nigel S
245 0 0 _aThe discovery of potent and long-acting oral factor Xa inhibitors with tetrahydroisoquinoline and benzazepine P4 motifs.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry letters
_cMar 2011
300 _a1588-92 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAdministration, Oral
650 0 4 _aAnimals
650 0 4 _aBenzazepines
_xadministration & dosage
650 0 4 _aCrystallography, X-Ray
650 0 4 _aDrug Evaluation, Preclinical
650 0 4 _aFactor Xa Inhibitors
650 0 4 _aMolecular Structure
650 0 4 _aRats
650 0 4 _aSerine Proteinase Inhibitors
_xadministration & dosage
650 0 4 _aTetrahydroisoquinolines
_xadministration & dosage
700 1 _aAdams, Carl
700 1 _aBelton, David
700 1 _aBrown, David
700 1 _aBurns-Kurtis, Cynthia L
700 1 _aChaudry, Laiq
700 1 _aChan, Chuen
700 1 _aConvery, Máire A
700 1 _aDavies, David E
700 1 _aExall, Anne M
700 1 _aHarling, John D
700 1 _aIrvine, Stephanie
700 1 _aIrving, Wendy R
700 1 _aKleanthous, Savvas
700 1 _aMcLay, Iain M
700 1 _aPateman, Anthony J
700 1 _aPatikis, Angela N
700 1 _aRoethke, Theresa J
700 1 _aSenger, Stefan
700 1 _aStelman, Gary J
700 1 _aToomey, John R
700 1 _aWest, Robert I
700 1 _aWhittaker, Caroline
700 1 _aZhou, Ping
700 1 _aYoung, Robert J
773 0 _tBioorganic & medicinal chemistry letters
_gvol. 21
_gno. 6
_gp. 1588-92
856 4 0 _uhttps://doi.org/10.1016/j.bmcl.2011.01.129
_zAvailable from publisher's website
999 _c20625132
_d20625132