| 000 | 01455 a2200397 4500 | ||
|---|---|---|---|
| 005 | 20250516024319.0 | ||
| 264 | 0 | _c20110826 | |
| 008 | 201108s 0 0 eng d | ||
| 022 | _a1550-7416 | ||
| 024 | 7 |
_a10.1208/s12248-011-9256-y _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aYu, Jing | |
| 245 | 0 | 0 |
_aFrom target selection to the minimum acceptable biological effect level for human study: use of mechanism-based PK/PD modeling to design safe and efficacious biologics. _h[electronic resource] |
| 260 |
_bThe AAPS journal _cJun 2011 |
||
| 300 |
_a169-78 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aAntibodies, Monoclonal _xadministration & dosage |
| 650 | 0 | 4 |
_aCytomegalovirus _ximmunology |
| 650 | 0 | 4 | _aDose-Response Relationship, Drug |
| 650 | 0 | 4 | _aDrug Delivery Systems |
| 650 | 0 | 4 | _aDrug Design |
| 650 | 0 | 4 | _aFeasibility Studies |
| 650 | 0 | 4 |
_aGlycoproteins _ximmunology |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aImmunologic Factors _xadministration & dosage |
| 650 | 0 | 4 | _aMacaca fascicularis |
| 650 | 0 | 4 | _aModels, Biological |
| 650 | 0 | 4 | _aSpecies Specificity |
| 650 | 0 | 4 |
_aTranslational Research, Biomedical _xmethods |
| 700 | 1 | _aKarcher, Helene | |
| 700 | 1 | _aFeire, Adam L | |
| 700 | 1 | _aLowe, Philip J | |
| 773 | 0 |
_tThe AAPS journal _gvol. 13 _gno. 2 _gp. 169-78 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1208/s12248-011-9256-y _zAvailable from publisher's website |
| 999 |
_c20613015 _d20613015 |
||