000 02320 a2200565 4500
005 20250516022534.0
264 0 _c20111115
008 201111s 0 0 eng d
022 _a1535-4989
024 7 _a10.1165/rcmb.2010-0240OC
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aNikam, Vandana S
245 0 0 _aTreprostinil inhibits the adhesion and differentiation of fibrocytes via the cyclic adenosine monophosphate-dependent and Ras-proximate protein-dependent inactivation of extracellular regulated kinase.
_h[electronic resource]
260 _bAmerican journal of respiratory cell and molecular biology
_cOct 2011
300 _a692-703 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aCell Adhesion
_xdrug effects
650 0 4 _aCell Differentiation
_xdrug effects
650 0 4 _aCells, Cultured
650 0 4 _aCyclic AMP
_xmetabolism
650 0 4 _aCyclic AMP Response Element-Binding Protein
_xmetabolism
650 0 4 _aCyclic AMP-Dependent Protein Kinases
_xmetabolism
650 0 4 _aEpoprostenol
_xanalogs & derivatives
650 0 4 _aExtracellular Matrix
_xmetabolism
650 0 4 _aExtracellular Signal-Regulated MAP Kinases
_xantagonists & inhibitors
650 0 4 _aFamilial Primary Pulmonary Hypertension
650 0 4 _aHumans
650 0 4 _aHypertension, Pulmonary
_xenzymology
650 0 4 _aIntegrin alpha5
_xmetabolism
650 0 4 _aIntegrin beta1
_xmetabolism
650 0 4 _aLeukocytes, Mononuclear
_xdrug effects
650 0 4 _aMutation
650 0 4 _aPhosphorylation
650 0 4 _aProtein Kinase Inhibitors
_xpharmacology
650 0 4 _aProto-Oncogene Proteins c-raf
_xmetabolism
650 0 4 _aReceptors, Prostaglandin
_xmetabolism
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aTime Factors
650 0 4 _aTransfection
650 0 4 _arap1 GTP-Binding Proteins
_xgenetics
650 0 4 _aras Proteins
_xmetabolism
700 1 _aWecker, Gesa
700 1 _aSchermuly, Ralph
700 1 _aRapp, Ulf
700 1 _aSzelepusa, Kirsten
700 1 _aSeeger, Werner
700 1 _aVoswinckel, Robert
773 0 _tAmerican journal of respiratory cell and molecular biology
_gvol. 45
_gno. 4
_gp. 692-703
856 4 0 _uhttps://doi.org/10.1165/rcmb.2010-0240OC
_zAvailable from publisher's website
999 _c20557961
_d20557961