000			01428 a2200349 4500
005			20250510215532.0
264		0	_c19780925
008			197809s 0 0 eng d
022			_a0022-2623
024	7		_a10.1021/jm00205a002 _2doi
040			_aNLM _beng _cNLM
100	1		_aPortoghese, P S
245	0	0	_a6beta-[N,N-Bis(2-chloroethyl)amino]-17-(cyclopropylmethyl)-4,5alpha-epoxy-3,14-dihydroxymorphinan(chlornaltrexamine) a potent opioid receptor alkylating agent with ultralong narcotic antagonist actitivty. _h[electronic resource]
260			_bJournal of medicinal chemistry _cJul 1978
300			_a598-9 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
650	0	4	_aAlkylating Agents _xchemical synthesis
650	0	4	_aAnalgesia
650	0	4	_aBinding, Competitive
650	0	4	_aMorphine _xantagonists & inhibitors
650	0	4	_aNaloxone _xanalogs & derivatives
650	0	4	_aNaltrexone _xanalogs & derivatives
650	0	4	_aNarcotic Antagonists _xchemical synthesis
650	0	4	_aNitrogen Mustard Compounds _xchemical synthesis
650	0	4	_aReceptors, Opioid _xdrug effects
700	1		_aLarson, D L
700	1		_aJiang, J B
700	1		_aTakemori, A E
700	1		_aCaruso, T P
773	0		_tJournal of medicinal chemistry _gvol. 21 _gno. 7 _gp. 598-9
856	4	0	_uhttps://doi.org/10.1021/jm00205a002 _zAvailable from publisher's website
999			_c204847 _d204847