| 000 | 01883 a2200517 4500 | ||
|---|---|---|---|
| 005 | 20250516014804.0 | ||
| 264 | 0 | _c20110614 | |
| 008 | 201106s 0 0 eng d | ||
| 022 | _a1521-009X | ||
| 024 | 7 |
_a10.1124/dmd.110.035071 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aMotta, Paola | |
| 245 | 0 | 0 |
_aCasopitant: in vitro data and SimCyp simulation to predict in vivo metabolic interactions involving cytochrome P450 3A4. _h[electronic resource] |
| 260 |
_bDrug metabolism and disposition: the biological fate of chemicals _cMar 2011 |
||
| 300 |
_a363-72 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aAdult |
| 650 | 0 | 4 | _aCells, Cultured |
| 650 | 0 | 4 | _aComputer Simulation |
| 650 | 0 | 4 |
_aCytochrome P-450 CYP3A _xgenetics |
| 650 | 0 | 4 | _aCytochrome P-450 CYP3A Inhibitors |
| 650 | 0 | 4 |
_aDrug Evaluation, Preclinical _xmethods |
| 650 | 0 | 4 | _aDrug Interactions |
| 650 | 0 | 4 |
_aEnzyme Induction _xdrug effects |
| 650 | 0 | 4 |
_aEnzyme Inhibitors _xpharmacology |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 |
_aHepatocytes _xdrug effects |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 |
_aMetabolic Clearance Rate _xdrug effects |
| 650 | 0 | 4 |
_aMicrosomes, Liver _xdrug effects |
| 650 | 0 | 4 | _aMiddle Aged |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 | _aNeurokinin-1 Receptor Antagonists |
| 650 | 0 | 4 |
_aNeurotransmitter Agents _xanalysis |
| 650 | 0 | 4 |
_aPiperazines _xanalysis |
| 650 | 0 | 4 |
_aPiperidines _xanalysis |
| 650 | 0 | 4 |
_aRecombinant Proteins _xantagonists & inhibitors |
| 650 | 0 | 4 | _aYoung Adult |
| 700 | 1 | _aPons, Nicoletta | |
| 700 | 1 | _aPagliarusco, Sabrina | |
| 700 | 1 | _aPellegatti, Mario | |
| 700 | 1 | _aBonomo, Fiorenza | |
| 773 | 0 |
_tDrug metabolism and disposition: the biological fate of chemicals _gvol. 39 _gno. 3 _gp. 363-72 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1124/dmd.110.035071 _zAvailable from publisher's website |
| 999 |
_c20439747 _d20439747 |
||