000 01617 a2200469 4500
005 20250516013959.0
264 0 _c20110815
008 201108s 0 0 eng d
022 _a1464-3405
024 7 _a10.1016/j.bmcl.2010.11.027
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBeck, Hilary P
245 0 0 _aImprovement of the synthesis and pharmacokinetic properties of chromenotriazolopyrimidine MDM2-p53 protein-protein inhibitors.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry letters
_cMay 2011
300 _a2752-5 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAnimals
650 0 4 _aDrug Stability
650 0 4 _aHumans
650 0 4 _aInfusion Pumps
650 0 4 _aInhibitory Concentration 50
650 0 4 _aMolecular Structure
650 0 4 _aProto-Oncogene Proteins c-mdm2
_xantagonists & inhibitors
650 0 4 _aPyrimidines
_xchemical synthesis
650 0 4 _aRats
650 0 4 _aSolubility
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTumor Suppressor Protein p53
_xantagonists & inhibitors
700 1 _aDeGraffenreid, Michael
700 1 _aFox, Brian
700 1 _aAllen, John G
700 1 _aRew, Yosup
700 1 _aSchneider, Stephen
700 1 _aSaiki, Anne Y
700 1 _aYu, Dongyin
700 1 _aOliner, Jonathan D
700 1 _aSalyers, Kevin
700 1 _aYe, Qiuping
700 1 _aOlson, Steven
773 0 _tBioorganic & medicinal chemistry letters
_gvol. 21
_gno. 9
_gp. 2752-5
856 4 0 _uhttps://doi.org/10.1016/j.bmcl.2010.11.027
_zAvailable from publisher's website
999 _c20414950
_d20414950