000 02046 a2200565 4500
005 20250516013533.0
264 0 _c20110120
008 201101s 0 0 eng d
022 _a1532-6535
024 7 _a10.1038/clpt.2010.250
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aJi, Y
245 0 0 _aGlycine and a glycine dehydrogenase (GLDC) SNP as citalopram/escitalopram response biomarkers in depression: pharmacometabolomics-informed pharmacogenomics.
_h[electronic resource]
260 _bClinical pharmacology and therapeutics
_cJan 2011
300 _a97-104 p.
_bdigital
500 _aPublication Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Validation Study
650 0 4 _aBiomarkers, Pharmacological
_xblood
650 0 4 _aCell Line
650 0 4 _aChromosomes, Human, Pair 9
_xgenetics
650 0 4 _aCitalopram
_xtherapeutic use
650 0 4 _aDNA-Binding Proteins
_xmetabolism
650 0 4 _aDepressive Disorder, Major
_xblood
650 0 4 _aDrug Monitoring
_xmethods
650 0 4 _aFemale
650 0 4 _aGenetic Association Studies
650 0 4 _aGlycine
_xblood
650 0 4 _aGlycine Dehydrogenase (Decarboxylating)
_xgenetics
650 0 4 _aHumans
650 0 4 _aIntrons
_xgenetics
650 0 4 _aLinkage Disequilibrium
650 0 4 _aMale
650 0 4 _aMetabolome
_xdrug effects
650 0 4 _aNuclear Proteins
_xmetabolism
650 0 4 _aPolymorphism, Single Nucleotide
650 0 4 _aSelective Serotonin Reuptake Inhibitors
_xtherapeutic use
700 1 _aHebbring, S
700 1 _aZhu, H
700 1 _aJenkins, G D
700 1 _aBiernacka, J
700 1 _aSnyder, K
700 1 _aDrews, M
700 1 _aFiehn, O
700 1 _aZeng, Z
700 1 _aSchaid, D
700 1 _aMrazek, D A
700 1 _aKaddurah-Daouk, R
700 1 _aWeinshilboum, R M
773 0 _tClinical pharmacology and therapeutics
_gvol. 89
_gno. 1
_gp. 97-104
856 4 0 _uhttps://doi.org/10.1038/clpt.2010.250
_zAvailable from publisher's website
999 _c20400415
_d20400415