000 02321 a2200661 4500
005 20250516013528.0
264 0 _c20110321
008 201103s 0 0 eng d
022 _a1528-0020
024 7 _a10.1182/blood-2010-04-278853
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aRoué, Gaël
245 0 0 _aThe Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78.
_h[electronic resource]
260 _bBlood
_cJan 2011
300 _a1270-9 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aAged, 80 and over
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aBenzoquinones
_xpharmacology
650 0 4 _aBoronic Acids
_xtherapeutic use
650 0 4 _aBortezomib
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aDown-Regulation
_xdrug effects
650 0 4 _aDrug Resistance, Neoplasm
_xdrug effects
650 0 4 _aEndoplasmic Reticulum Chaperone BiP
650 0 4 _aFemale
650 0 4 _aGene Expression Regulation, Neoplastic
_xdrug effects
650 0 4 _aGene Knockdown Techniques
650 0 4 _aHSP90 Heat-Shock Proteins
_xantagonists & inhibitors
650 0 4 _aHeat-Shock Proteins
_xgenetics
650 0 4 _aHumans
650 0 4 _aLactams, Macrocyclic
_xpharmacology
650 0 4 _aLymphoma, Mantle-Cell
_xdrug therapy
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, SCID
650 0 4 _aMice, Transgenic
650 0 4 _aMiddle Aged
650 0 4 _aMolecular Chaperones
_xgenetics
650 0 4 _aPyrazines
_xtherapeutic use
650 0 4 _aReceptors, Estrogen
_xmetabolism
650 0 4 _aTumor Cells, Cultured
650 0 4 _aXenograft Model Antitumor Assays
700 1 _aPérez-Galán, Patricia
700 1 _aMozos, Ana
700 1 _aLópez-Guerra, Mónica
700 1 _aXargay-Torrent, Sílvia
700 1 _aRosich, Laia
700 1 _aSaborit-Villarroya, Ifigènia
700 1 _aNormant, Emmanuel
700 1 _aCampo, Elias
700 1 _aColomer, Dolors
773 0 _tBlood
_gvol. 117
_gno. 4
_gp. 1270-9
856 4 0 _uhttps://doi.org/10.1182/blood-2010-04-278853
_zAvailable from publisher's website
999 _c20400119
_d20400119