000 02022 a2200589 4500
005 20250516011903.0
264 0 _c20110314
008 201103s 0 0 eng d
022 _a1464-3405
024 7 _a10.1016/j.bmcl.2010.10.035
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aReddy, P Ganapati
245 0 0 _a2'-deoxy-2'-α-fluoro-2'-β-C-methyl 3',5'-cyclic phosphate nucleotide prodrug analogs as inhibitors of HCV NS5B polymerase: discovery of PSI-352938.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry letters
_cDec 2010
300 _a7376-80 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAdministration, Oral
650 0 4 _aAnimals
650 0 4 _aAntiviral Agents
_xchemistry
650 0 4 _aCell Line, Tumor
650 0 4 _aCrystallography, X-Ray
650 0 4 _aCyclic P-Oxides
_xchemistry
650 0 4 _aEnzyme Inhibitors
_xchemistry
650 0 4 _aHepacivirus
_xenzymology
650 0 4 _aHumans
650 0 4 _aMolecular Conformation
650 0 4 _aNucleosides
_xchemistry
650 0 4 _aNucleotides, Cyclic
_xchemical synthesis
650 0 4 _aProdrugs
_xchemistry
650 0 4 _aRats
650 0 4 _aStructure-Activity Relationship
650 0 4 _aViral Nonstructural Proteins
_xantagonists & inhibitors
700 1 _aBao, Donghui
700 1 _aChang, Wonsuk
700 1 _aChun, Byoung-Kwon
700 1 _aDu, Jinfa
700 1 _aNagarathnam, Dhanapalan
700 1 _aRachakonda, Suguna
700 1 _aRoss, Bruce S
700 1 _aZhang, Hai-Ren
700 1 _aBansal, Shalini
700 1 _aEspiritu, Christine L
700 1 _aKeilman, Meg
700 1 _aLam, Angela M
700 1 _aNiu, Congrong
700 1 _aSteuer, Holly Micolochick
700 1 _aFurman, Phillip A
700 1 _aOtto, Michael J
700 1 _aSofia, Michael J
773 0 _tBioorganic & medicinal chemistry letters
_gvol. 20
_gno. 24
_gp. 7376-80
856 4 0 _uhttps://doi.org/10.1016/j.bmcl.2010.10.035
_zAvailable from publisher's website
999 _c20349778
_d20349778