000 02098 a2200589 4500
005 20250516005813.0
264 0 _c20120611
008 201206s 0 0 eng d
022 _a1573-0646
024 7 _a10.1007/s10637-010-9568-2
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aOh, Eun-Taex
245 0 0 _aNovel histone deacetylase inhibitor CG200745 induces clonogenic cell death by modulating acetylation of p53 in cancer cells.
_h[electronic resource]
260 _bInvestigational new drugs
_cApr 2012
300 _a435-42 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAcetylation
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aCell Death
_xdrug effects
650 0 4 _aCell Line, Tumor
650 0 4 _aColorectal Neoplasms
_xgenetics
650 0 4 _aCyclin-Dependent Kinase Inhibitor p21
_xgenetics
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aGene Expression Regulation, Neoplastic
_xdrug effects
650 0 4 _aGenes, Reporter
650 0 4 _aHalf-Life
650 0 4 _aHistone Deacetylase Inhibitors
_xpharmacology
650 0 4 _aHistone Deacetylases
_xmetabolism
650 0 4 _aHistones
_xmetabolism
650 0 4 _aHumans
650 0 4 _aHydroxamic Acids
_xpharmacology
650 0 4 _aLysine
650 0 4 _aMale
650 0 4 _aMutation
650 0 4 _aNaphthalenes
_xpharmacology
650 0 4 _aProstatic Neoplasms
_xgenetics
650 0 4 _aProtein Stability
650 0 4 _aProto-Oncogene Proteins c-mdm2
_xgenetics
650 0 4 _aTime Factors
650 0 4 _aTranscriptional Activation
_xdrug effects
650 0 4 _aTransfection
650 0 4 _aTumor Stem Cell Assay
650 0 4 _aTumor Suppressor Protein p53
_xgenetics
700 1 _aPark, Moon-Taek
700 1 _aChoi, Bo-Hwa
700 1 _aRo, Seonggu
700 1 _aChoi, Eun-Kyung
700 1 _aJeong, Seong-Yun
700 1 _aPark, Heon Joo
773 0 _tInvestigational new drugs
_gvol. 30
_gno. 2
_gp. 435-42
856 4 0 _uhttps://doi.org/10.1007/s10637-010-9568-2
_zAvailable from publisher's website
999 _c20279659
_d20279659