000			01905 a2200541 4500
005			20250516005639.0
264		0	_c20101230
008			201012s 0 0 eng d
022			_a1520-4804
024	7		_a10.1021/jm100780c _2doi
040			_aNLM _beng _cNLM
100	1		_aChou, Li-Chen
245	0	0	_aDesign, synthesis, and preclinical evaluation of new 5,6- (or 6,7-) disubstituted-2-(fluorophenyl)quinolin-4-one derivatives as potent antitumor agents. _h[electronic resource]
260			_bJournal of medicinal chemistry _cNov 2010
300			_a8047-58 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650	0	4	_aAnimals
650	0	4	_aAntineoplastic Agents _xchemical synthesis
650	0	4	_aCell Line, Tumor
650	0	4	_aCell Proliferation _xdrug effects
650	0	4	_aDrug Design
650	0	4	_aDrug Screening Assays, Antitumor
650	0	4	_aHumans
650	0	4	_aInsulin-Like Growth Factor Binding Protein 1 _xmetabolism
650	0	4	_aMale
650	0	4	_aMice
650	0	4	_aMice, Nude
650	0	4	_aModels, Molecular
650	0	4	_aNeoplasm Transplantation
650	0	4	_aOrganophosphates _xchemical synthesis
650	0	4	_aPhosphorylation
650	0	4	_aQuinolones _xchemical synthesis
650	0	4	_aStructure-Activity Relationship
650	0	4	_aTransplantation, Heterologous
700	1		_aTsai, Meng-Tung
700	1		_aHsu, Mei-Hua
700	1		_aWang, Sheng-Hung
700	1		_aWay, Tzong-Der
700	1		_aHuang, Chi-Hung
700	1		_aLin, Hui-Yi
700	1		_aQian, Keduo
700	1		_aDong, Yizhou
700	1		_aLee, Kuo-Hsiung
700	1		_aHuang, Li-Jiau
700	1		_aKuo, Sheng-Chu
773	0		_tJournal of medicinal chemistry _gvol. 53 _gno. 22 _gp. 8047-58
856	4	0	_uhttps://doi.org/10.1021/jm100780c _zAvailable from publisher's website
999			_c20274568 _d20274568