| 000 | 01751 a2200457 4500 | ||
|---|---|---|---|
| 005 | 20250516004330.0 | ||
| 264 | 0 | _c20110705 | |
| 008 | 201107s 0 0 eng d | ||
| 022 | _a1521-009X | ||
| 024 | 7 |
_a10.1124/dmd.110.035493 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aGhosal, Anima | |
| 245 | 0 | 0 |
_aIdentification of human liver cytochrome P450 enzymes involved in the metabolism of SCH 530348 (Vorapaxar), a potent oral thrombin protease-activated receptor 1 antagonist. _h[electronic resource] |
| 260 |
_bDrug metabolism and disposition: the biological fate of chemicals _cJan 2011 |
||
| 300 |
_a30-8 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 |
_aAstemizole _xpharmacology |
| 650 | 0 | 4 |
_aCytochrome P-450 CYP3A _xmetabolism |
| 650 | 0 | 4 |
_aCytochrome P-450 Enzyme System _xmetabolism |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aHydroxylation |
| 650 | 0 | 4 |
_aKetoconazole _xpharmacology |
| 650 | 0 | 4 |
_aLactones _xblood |
| 650 | 0 | 4 |
_aMicrosomes _xmetabolism |
| 650 | 0 | 4 |
_aMicrosomes, Liver _xmetabolism |
| 650 | 0 | 4 |
_aPyridines _xblood |
| 650 | 0 | 4 |
_aReceptor, PAR-1 _xmetabolism |
| 650 | 0 | 4 |
_aReceptors, Thrombin _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aRecombinant Proteins _xmetabolism |
| 650 | 0 | 4 |
_aTranylcypromine _xpharmacology |
| 650 | 0 | 4 | _aPlatelet Aggregation Inhibitors |
| 700 | 1 | _aLu, Xiaowen | |
| 700 | 1 | _aPenner, Natalia | |
| 700 | 1 | _aGao, Lan | |
| 700 | 1 | _aRamanathan, Ragu | |
| 700 | 1 | _aChowdhury, Swapan K | |
| 700 | 1 | _aKishnani, Narendra S | |
| 700 | 1 | _aAlton, Kevin B | |
| 773 | 0 |
_tDrug metabolism and disposition: the biological fate of chemicals _gvol. 39 _gno. 1 _gp. 30-8 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1124/dmd.110.035493 _zAvailable from publisher's website |
| 999 |
_c20232445 _d20232445 |
||