000			02117 a2200661 4500
005			20250516002554.0
264		0	_c20101109
008			201011s 0 0 eng d
022			_a1520-4804
024	7		_a10.1021/jm100863x _2doi
040			_aNLM _beng _cNLM
100	1		_aSofia, Michael J
245	0	0	_aDiscovery of a β-d-2'-deoxy-2'-α-fluoro-2'-β-C-methyluridine nucleotide prodrug (PSI-7977) for the treatment of hepatitis C virus. _h[electronic resource]
260			_bJournal of medicinal chemistry _cOct 2010
300			_a7202-18 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aAnimals
650	0	4	_aAntiviral Agents _xchemical synthesis
650	0	4	_aCell Line
650	0	4	_aCrystallography, X-Ray
650	0	4	_aDogs
650	0	4	_aDrug Resistance, Viral
650	0	4	_aEsters
650	0	4	_aHepacivirus _xdrug effects
650	0	4	_aHepatocytes _xmetabolism
650	0	4	_aHumans
650	0	4	_aIn Vitro Techniques
650	0	4	_aLiver _xmetabolism
650	0	4	_aMacaca fascicularis
650	0	4	_aMutation
650	0	4	_aProdrugs _xchemical synthesis
650	0	4	_aRats
650	0	4	_aReplicon
650	0	4	_aSofosbuvir
650	0	4	_aStereoisomerism
650	0	4	_aStructure-Activity Relationship
650	0	4	_aUridine Monophosphate _xanalogs & derivatives
650	0	4	_aViral Nonstructural Proteins _xantagonists & inhibitors
700	1		_aBao, Donghui
700	1		_aChang, Wonsuk
700	1		_aDu, Jinfa
700	1		_aNagarathnam, Dhanapalan
700	1		_aRachakonda, Suguna
700	1		_aReddy, P Ganapati
700	1		_aRoss, Bruce S
700	1		_aWang, Peiyuan
700	1		_aZhang, Hai-Ren
700	1		_aBansal, Shalini
700	1		_aEspiritu, Christine
700	1		_aKeilman, Meg
700	1		_aLam, Angela M
700	1		_aSteuer, Holly M Micolochick
700	1		_aNiu, Congrong
700	1		_aOtto, Michael J
700	1		_aFurman, Phillip A
773	0		_tJournal of medicinal chemistry _gvol. 53 _gno. 19 _gp. 7202-18
856	4	0	_uhttps://doi.org/10.1021/jm100863x _zAvailable from publisher's website
999			_c20176445 _d20176445