000 01647 a2200457 4500
005 20250516002107.0
264 0 _c20101230
008 201012s 0 0 eng d
022 _a1873-3778
024 7 _a10.1016/j.chroma.2010.08.044
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aWang, Shiyi
245 0 0 _aSeparation of post-translational modifications in monoclonal antibodies by exploiting subtle conformational changes under mildly acidic conditions.
_h[electronic resource]
260 _bJournal of chromatography. A
_cOct 2010
300 _a6496-502 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAntibodies, Monoclonal
_xchemistry
650 0 4 _aCalorimetry, Differential Scanning
650 0 4 _aChromatography, High Pressure Liquid
_xmethods
650 0 4 _aChromatography, Ion Exchange
_xmethods
650 0 4 _aCircular Dichroism
650 0 4 _aGlycosylation
650 0 4 _aHumans
650 0 4 _aHydrogen-Ion Concentration
650 0 4 _aMethionine
_xchemistry
650 0 4 _aModels, Molecular
650 0 4 _aOxidation-Reduction
650 0 4 _aPeptide Mapping
650 0 4 _aProtein Conformation
650 0 4 _aProtein Denaturation
650 0 4 _aProtein Processing, Post-Translational
650 0 4 _aSpectrophotometry, Ultraviolet
650 0 4 _aTemperature
700 1 _aIonescu, Roxana
700 1 _aPeekhaus, Norbert
700 1 _aLeung, Jin-Yu
700 1 _aHa, Sha
700 1 _aVlasak, Josef
773 0 _tJournal of chromatography. A
_gvol. 1217
_gno. 42
_gp. 6496-502
856 4 0 _uhttps://doi.org/10.1016/j.chroma.2010.08.044
_zAvailable from publisher's website
999 _c20160917
_d20160917