000 01510 a2200409 4500
005 20250516001951.0
264 0 _c20101206
008 201012s 0 0 eng d
022 _a1089-8638
024 7 _a10.1016/j.jmb.2010.08.008
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aCampeotto, Ivan
245 0 0 _aStructural insights into substrate specificity in variants of N-acetylneuraminic Acid lyase produced by directed evolution.
_h[electronic resource]
260 _bJournal of molecular biology
_cNov 2010
300 _a56-69 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAmino Acid Substitution
650 0 4 _aCrystallography, X-Ray
650 0 4 _aDirected Molecular Evolution
650 0 4 _aEscherichia coli Proteins
_xchemistry
650 0 4 _aModels, Molecular
650 0 4 _aMutant Proteins
_xchemistry
650 0 4 _aMutation, Missense
650 0 4 _aOxo-Acid-Lyases
_xchemistry
650 0 4 _aProtein Structure, Tertiary
650 0 4 _aSubstrate Specificity
700 1 _aBolt, Amanda H
700 1 _aHarman, Thomas A
700 1 _aDennis, Caitriona
700 1 _aTrinh, Chi H
700 1 _aPhillips, Simon E V
700 1 _aNelson, Adam
700 1 _aPearson, Arwen R
700 1 _aBerry, Alan
773 0 _tJournal of molecular biology
_gvol. 404
_gno. 1
_gp. 56-69
856 4 0 _uhttps://doi.org/10.1016/j.jmb.2010.08.008
_zAvailable from publisher's website
999 _c20158508
_d20158508