000 01892 a2200493 4500
005 20250516001557.0
264 0 _c20110106
008 201101s 0 0 eng d
022 _a1096-9098
024 7 _a10.1002/jso.21661
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLu, Xinchang
245 0 0 _aSorafenib induces growth inhibition and apoptosis of human chondrosarcoma cells by blocking the RAF/ERK/MEK pathway.
_h[electronic resource]
260 _bJournal of surgical oncology
_cDec 2010
300 _a821-6 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aApoptosis Regulatory Proteins
_xmetabolism
650 0 4 _aBenzenesulfonates
_xpharmacology
650 0 4 _aBlotting, Western
650 0 4 _aBone Neoplasms
_xdrug therapy
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aChondrosarcoma
_xdrug therapy
650 0 4 _aCyclin D1
_xmetabolism
650 0 4 _aExtracellular Signal-Regulated MAP Kinases
_xantagonists & inhibitors
650 0 4 _aHumans
650 0 4 _aMitogen-Activated Protein Kinase Kinases
_xantagonists & inhibitors
650 0 4 _aNiacinamide
_xanalogs & derivatives
650 0 4 _aPhenylurea Compounds
650 0 4 _aPhosphorylation
_xdrug effects
650 0 4 _aProtein Kinase Inhibitors
_xpharmacology
650 0 4 _aProto-Oncogene Proteins c-bcl-2
_xmetabolism
650 0 4 _aPyridines
_xpharmacology
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aSorafenib
650 0 4 _araf Kinases
_xantagonists & inhibitors
700 1 _aTang, Xiaodong
700 1 _aGuo, Wei
700 1 _aRen, Tingting
700 1 _aZhao, Hui
773 0 _tJournal of surgical oncology
_gvol. 102
_gno. 7
_gp. 821-6
856 4 0 _uhttps://doi.org/10.1002/jso.21661
_zAvailable from publisher's website
999 _c20145413
_d20145413