000 01144 a2200337 4500
005 20250511215641.0
264 0 _c19910501
008 199105s 0 0 eng d
022 _a0021-9258
040 _aNLM
_beng
_cNLM
100 1 _aMcCloskey, D E
245 0 0 _aDecreased folylpolyglutamate synthetase activity as a mechanism of methotrexate resistance in CCRF-CEM human leukemia sublines.
_h[electronic resource]
260 _bThe Journal of biological chemistry
_cApr 1991
300 _a6181-7 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aDrug Resistance
650 0 4 _aHumans
650 0 4 _aLeukemia
_xenzymology
650 0 4 _aMethotrexate
_xmetabolism
650 0 4 _aPeptide Synthases
_xmetabolism
650 0 4 _aPhenotype
650 0 4 _aThymidylate Synthase
_xmetabolism
650 0 4 _aTumor Cells, Cultured
700 1 _aMcGuire, J J
700 1 _aRussell, C A
700 1 _aRowan, B G
700 1 _aBertino, J R
700 1 _aPizzorno, G
700 1 _aMini, E
773 0 _tThe Journal of biological chemistry
_gvol. 266
_gno. 10
_gp. 6181-7
999 _c2013758
_d2013758