000 | 01144 a2200337 4500 | ||
---|---|---|---|
005 | 20250511215641.0 | ||
264 | 0 | _c19910501 | |
008 | 199105s 0 0 eng d | ||
022 | _a0021-9258 | ||
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aMcCloskey, D E | |
245 | 0 | 0 |
_aDecreased folylpolyglutamate synthetase activity as a mechanism of methotrexate resistance in CCRF-CEM human leukemia sublines. _h[electronic resource] |
260 |
_bThe Journal of biological chemistry _cApr 1991 |
||
300 |
_a6181-7 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, U.S. Gov't, P.H.S. | ||
650 | 0 | 4 | _aDrug Resistance |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 |
_aLeukemia _xenzymology |
650 | 0 | 4 |
_aMethotrexate _xmetabolism |
650 | 0 | 4 |
_aPeptide Synthases _xmetabolism |
650 | 0 | 4 | _aPhenotype |
650 | 0 | 4 |
_aThymidylate Synthase _xmetabolism |
650 | 0 | 4 | _aTumor Cells, Cultured |
700 | 1 | _aMcGuire, J J | |
700 | 1 | _aRussell, C A | |
700 | 1 | _aRowan, B G | |
700 | 1 | _aBertino, J R | |
700 | 1 | _aPizzorno, G | |
700 | 1 | _aMini, E | |
773 | 0 |
_tThe Journal of biological chemistry _gvol. 266 _gno. 10 _gp. 6181-7 |
|
999 |
_c2013758 _d2013758 |