000 01736 a2200457 4500
005 20250516001228.0
264 0 _c20101020
008 201010s 0 0 eng d
022 _a1879-3169
024 7 _a10.1016/j.toxlet.2010.08.011
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aZhang, Xiaoyu
245 0 0 _aPYDDT, a novel phase 2 enzymes inducer, activates Keap1-Nrf2 pathway via depleting the cellular level of glutathione.
_h[electronic resource]
260 _bToxicology letters
_cNov 2010
300 _a93-101 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdaptor Proteins, Signal Transducing
_xbiosynthesis
650 0 4 _aAnimals
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Survival
650 0 4 _aCytoskeletal Proteins
_xbiosynthesis
650 0 4 _aDrugs, Chinese Herbal
_xchemistry
650 0 4 _aEnzyme Induction
650 0 4 _aGlutathione
_xmetabolism
650 0 4 _aHepatocytes
_xdrug effects
650 0 4 _aKelch-Like ECH-Associated Protein 1
650 0 4 _aMetabolic Detoxication, Phase II
650 0 4 _aMice
650 0 4 _aNF-E2-Related Factor 2
_xbiosynthesis
650 0 4 _aOxidative Stress
_xdrug effects
650 0 4 _aPlant Extracts
_xpharmacology
650 0 4 _aPlants, Medicinal
_xchemistry
650 0 4 _aProtein Processing, Post-Translational
_xdrug effects
650 0 4 _aReactive Oxygen Species
_xmetabolism
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aThiophenes
_xchemistry
700 1 _aZhao, Xiaofeng
700 1 _aMa, Zhongjun
773 0 _tToxicology letters
_gvol. 199
_gno. 1
_gp. 93-101
856 4 0 _uhttps://doi.org/10.1016/j.toxlet.2010.08.011
_zAvailable from publisher's website
999 _c20134384
_d20134384