000 01875 a2200541 4500
005 20250515235306.0
264 0 _c20101207
008 201012s 0 0 eng d
022 _a1521-0111
024 7 _a10.1124/mol.110.066076
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aEich, Marcus
245 0 0 _aNijmegen breakage syndrome protein (NBN) causes resistance to methylating anticancer drugs such as temozolomide.
_h[electronic resource]
260 _bMolecular pharmacology
_cNov 2010
300 _a943-51 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAntineoplastic Agents, Alkylating
_xpharmacology
650 0 4 _aApoptosis
650 0 4 _aCaspase 7
_xmetabolism
650 0 4 _aCell Cycle Proteins
_xgenetics
650 0 4 _aCell Line, Transformed
650 0 4 _aCell Line, Tumor
650 0 4 _aDNA Methylation
650 0 4 _aDacarbazine
_xanalogs & derivatives
650 0 4 _aDrug Resistance, Neoplasm
650 0 4 _aFibroblasts
_xdrug effects
650 0 4 _aGuanine
_xanalogs & derivatives
650 0 4 _aHomozygote
650 0 4 _aHumans
650 0 4 _aMelanoma
650 0 4 _aMethylnitronitrosoguanidine
_xpharmacology
650 0 4 _aMutagens
_xpharmacology
650 0 4 _aMutation
650 0 4 _aNecrosis
650 0 4 _aNijmegen Breakage Syndrome
_xpathology
650 0 4 _aNuclear Proteins
_xgenetics
650 0 4 _aPoly (ADP-Ribose) Polymerase-1
650 0 4 _aPoly(ADP-ribose) Polymerases
_xmetabolism
650 0 4 _aTemozolomide
650 0 4 _aUveal Neoplasms
650 0 4 _aUveal Melanoma
700 1 _aRoos, Wynand P
700 1 _aDianov, Grigory L
700 1 _aDigweed, Martin
700 1 _aKaina, Bernd
773 0 _tMolecular pharmacology
_gvol. 78
_gno. 5
_gp. 943-51
856 4 0 _uhttps://doi.org/10.1124/mol.110.066076
_zAvailable from publisher's website
999 _c20064778
_d20064778