000 03058 a2200865 4500
005 20250515234756.0
264 0 _c20101022
008 201010s 0 0 eng d
022 _a1476-4679
024 7 _a10.1038/ncb2090
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLuciani, Alessandro
245 0 0 _aDefective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition.
_h[electronic resource]
260 _bNature cell biology
_cSep 2010
300 _a863-75 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAcetylcysteine
_xpharmacology
650 0 4 _aAdaptor Proteins, Signal Transducing
_xgenetics
650 0 4 _aAdolescent
650 0 4 _aAdult
650 0 4 _aAnimals
650 0 4 _aAntioxidants
_xpharmacology
650 0 4 _aApoptosis Regulatory Proteins
_xgenetics
650 0 4 _aAutophagy
_xdrug effects
650 0 4 _aBeclin-1
650 0 4 _aCell Line
650 0 4 _aCystamine
_xpharmacology
650 0 4 _aCystic Fibrosis
_xdrug therapy
650 0 4 _aCystic Fibrosis Transmembrane Conductance Regulator
_xantagonists & inhibitors
650 0 4 _aEpithelial Sodium Channels
_xgenetics
650 0 4 _aGTP-Binding Proteins
650 0 4 _aHeat-Shock Proteins
_xmetabolism
650 0 4 _aHumans
650 0 4 _aInflammation
_xmetabolism
650 0 4 _aMembrane Proteins
_xgenetics
650 0 4 _aMice
650 0 4 _aMice, Inbred CFTR
650 0 4 _aMice, Inbred Strains
650 0 4 _aMice, Transgenic
650 0 4 _aMicrotubule-Associated Proteins
_xmetabolism
650 0 4 _aModels, Biological
650 0 4 _aNasal Polyps
_xdrug therapy
650 0 4 _aOrganometallic Compounds
_xpharmacology
650 0 4 _aPhosphatidylinositol 3-Kinases
_xmetabolism
650 0 4 _aPhosphoinositide-3 Kinase Inhibitors
650 0 4 _aProtein Binding
_xphysiology
650 0 4 _aProtein Glutamine gamma Glutamyltransferase 2
650 0 4 _aProtein Transport
_xgenetics
650 0 4 _aReactive Oxygen Species
_xantagonists & inhibitors
650 0 4 _aRespiratory Mucosa
_xcytology
650 0 4 _aSalicylates
_xpharmacology
650 0 4 _aSequestosome-1 Protein
650 0 4 _aSmall Ubiquitin-Related Modifier Proteins
_xmetabolism
650 0 4 _aTransglutaminases
_xgenetics
650 0 4 _aYoung Adult
700 1 _aVillella, Valeria Rachela
700 1 _aEsposito, Speranza
700 1 _aBrunetti-Pierri, Nicola
700 1 _aMedina, Diego
700 1 _aSettembre, Carmine
700 1 _aGavina, Manuela
700 1 _aPulze, Laura
700 1 _aGiardino, Ida
700 1 _aPettoello-Mantovani, Massimo
700 1 _aD'Apolito, Maria
700 1 _aGuido, Stefano
700 1 _aMasliah, Eliezer
700 1 _aSpencer, Brian
700 1 _aQuaratino, Sonia
700 1 _aRaia, Valeria
700 1 _aBallabio, Andrea
700 1 _aMaiuri, Luigi
773 0 _tNature cell biology
_gvol. 12
_gno. 9
_gp. 863-75
856 4 0 _uhttps://doi.org/10.1038/ncb2090
_zAvailable from publisher's website
999 _c20047558
_d20047558