000 01603 a2200433 4500
005 20250515234628.0
264 0 _c20101228
008 201012s 0 0 eng d
022 _a1768-3254
024 7 _a10.1016/j.ejmech.2010.07.029
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSoares, Maria I L
245 0 0 _aChiral 6-hydroxymethyl-1H,3H-pyrrolo[1,2-c]thiazoles: novel antitumor DNA monoalkylating agents.
_h[electronic resource]
260 _bEuropean journal of medicinal chemistry
_cOct 2010
300 _a4676-81 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdenocarcinoma
_xdrug therapy
650 0 4 _aAntineoplastic Agents, Alkylating
_xchemical synthesis
650 0 4 _aBreast Neoplasms
_xdrug therapy
650 0 4 _aCell Line, Tumor
650 0 4 _aColorectal Neoplasms
_xdrug therapy
650 0 4 _aDNA
_xmetabolism
650 0 4 _aDrug Screening Assays, Antitumor
650 0 4 _aFemale
650 0 4 _aHumans
650 0 4 _aMelanoma
_xdrug therapy
650 0 4 _aPyrroles
_xchemical synthesis
650 0 4 _aThiazoles
_xchemical synthesis
700 1 _aBrito, Ana Filipa
700 1 _aLaranjo, Mafalda
700 1 _aAbrantes, Ana Margarida
700 1 _aBotelho, M Filomena
700 1 _aPaixão, José A
700 1 _aBeja, Ana Matos
700 1 _aSilva, Manuela Ramos
700 1 _aPinho E Melo, Teresa M V D
773 0 _tEuropean journal of medicinal chemistry
_gvol. 45
_gno. 10
_gp. 4676-81
856 4 0 _uhttps://doi.org/10.1016/j.ejmech.2010.07.029
_zAvailable from publisher's website
999 _c20042866
_d20042866