000			01934 a2200589 4500
005			20250515233442.0
264		0	_c20101230
008			201012s 0 0 eng d
022			_a1464-3391
024	7		_a10.1016/j.bmc.2010.06.031 _2doi
040			_aNLM _beng _cNLM
100	1		_aNiculescu-Duvaz, Dan
245	0	0	_aNovel tricyclic pyrazole BRAF inhibitors with imidazole or furan central scaffolds. _h[electronic resource]
260			_bBioorganic & medicinal chemistry _cSep 2010
300			_a6934-52 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_aAnimals
650	0	4	_aBinding Sites
650	0	4	_aComputer Simulation
650	0	4	_aFemale
650	0	4	_aFurans _xchemistry
650	0	4	_aHumans
650	0	4	_aImidazoles _xchemistry
650	0	4	_aMice
650	0	4	_aMutation
650	0	4	_aProtein Kinase Inhibitors _xchemical synthesis
650	0	4	_aProtein Structure, Tertiary
650	0	4	_aProto-Oncogene Proteins B-raf _xantagonists & inhibitors
650	0	4	_aPyrazoles _xchemical synthesis
650	0	4	_aStructure-Activity Relationship
700	1		_aNiculescu-Duvaz, Ion
700	1		_aSuijkerbuijk, Bart M J M
700	1		_aMénard, Delphine
700	1		_aZambon, Alfonso
700	1		_aNourry, Arnaud
700	1		_aDavies, Lawrence
700	1		_aManne, Helen A
700	1		_aFriedlos, Frank
700	1		_aOgilvie, Lesley
700	1		_aHedley, Douglas
700	1		_aTakle, Andrew K
700	1		_aWilson, David M
700	1		_aPons, Jean-Francois
700	1		_aCoulter, Tom
700	1		_aKirk, Ruth
700	1		_aCantarino, Neus
700	1		_aWhittaker, Steven
700	1		_aMarais, Richard
700	1		_aSpringer, Caroline J
773	0		_tBioorganic & medicinal chemistry _gvol. 18 _gno. 18 _gp. 6934-52
856	4	0	_uhttps://doi.org/10.1016/j.bmc.2010.06.031 _zAvailable from publisher's website
999			_c20007549 _d20007549