000 01931 a2200541 4500
005 20250515232621.0
264 0 _c20110104
008 201101s 0 0 eng d
022 _a1096-0929
024 7 _a10.1093/toxsci/kfq220
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aRotroff, Daniel M
245 0 0 _aIncorporating human dosimetry and exposure into high-throughput in vitro toxicity screening.
_h[electronic resource]
260 _bToxicological sciences : an official journal of the Society of Toxicology
_cOct 2010
300 _a348-58 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
650 0 4 _aCells, Cultured
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aFemale
650 0 4 _aGas Chromatography-Mass Spectrometry
650 0 4 _aHepatocytes
_xdrug effects
650 0 4 _aHigh-Throughput Screening Assays
_xmethods
650 0 4 _aHumans
650 0 4 _aMale
650 0 4 _aMetabolic Clearance Rate
650 0 4 _aProtein Binding
_xdrug effects
650 0 4 _aRisk Assessment
650 0 4 _aToxicity Tests
650 0 4 _aXenobiotics
_xclassification
700 1 _aWetmore, Barbara A
700 1 _aDix, David J
700 1 _aFerguson, Stephen S
700 1 _aClewell, Harvey J
700 1 _aHouck, Keith A
700 1 _aLecluyse, Edward L
700 1 _aAndersen, Melvin E
700 1 _aJudson, Richard S
700 1 _aSmith, Cornelia M
700 1 _aSochaski, Mark A
700 1 _aKavlock, Robert J
700 1 _aBoellmann, Frank
700 1 _aMartin, Matthew T
700 1 _aReif, David M
700 1 _aWambaugh, John F
700 1 _aThomas, Russell S
773 0 _tToxicological sciences : an official journal of the Society of Toxicology
_gvol. 117
_gno. 2
_gp. 348-58
856 4 0 _uhttps://doi.org/10.1093/toxsci/kfq220
_zAvailable from publisher's website
999 _c19981635
_d19981635