000 01730 a2200445 4500
005 20250515232040.0
264 0 _c20110714
008 201107s 0 0 eng d
022 _a1552-4604
024 7 _a10.1177/0091270010370588
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBavisotto, Linda M
245 0 0 _aTecarfarin, a novel vitamin K reductase antagonist, is not affected by CYP2C9 and CYP3A4 inhibition following concomitant administration of fluconazole in healthy participants.
_h[electronic resource]
260 _bJournal of clinical pharmacology
_cApr 2011
300 _a561-74 p.
_bdigital
500 _aPublication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
650 0 4 _aAdministration, Oral
650 0 4 _aAdult
650 0 4 _aAryl Hydrocarbon Hydroxylases
_xantagonists & inhibitors
650 0 4 _aBenzoates
_xadministration & dosage
650 0 4 _aCoumarins
_xadministration & dosage
650 0 4 _aCytochrome P-450 CYP2C9
650 0 4 _aCytochrome P-450 CYP3A
650 0 4 _aCytochrome P-450 CYP3A Inhibitors
650 0 4 _aDrug Interactions
650 0 4 _aEnzyme Inhibitors
_xpharmacology
650 0 4 _aFemale
650 0 4 _aFluconazole
_xpharmacology
650 0 4 _aHumans
650 0 4 _aMale
650 0 4 _aNAD(P)H Dehydrogenase (Quinone)
_xantagonists & inhibitors
650 0 4 _aWarfarin
_xadministration & dosage
700 1 _aEllis, David J
700 1 _aMilner, Peter G
700 1 _aCombs, Daniel L
700 1 _aIrwin, Ian
700 1 _aCanafax, Daniel M
773 0 _tJournal of clinical pharmacology
_gvol. 51
_gno. 4
_gp. 561-74
856 4 0 _uhttps://doi.org/10.1177/0091270010370588
_zAvailable from publisher's website
999 _c19965344
_d19965344