000 02049 a2200553 4500
005 20250515231814.0
264 0 _c20101103
008 201011s 0 0 eng d
022 _a1432-0738
024 7 _a10.1007/s00204-010-0572-2
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aElcombe, Clifford R
245 0 0 _aHepatocellular hypertrophy and cell proliferation in Sprague-Dawley rats following dietary exposure to ammonium perfluorooctanoate occurs through increased activation of the xenosensor nuclear receptors PPARα and CAR/PXR.
_h[electronic resource]
260 _bArchives of toxicology
_cOct 2010
300 _a787-98 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aBody Weight
_xdrug effects
650 0 4 _aCaprylates
_xtoxicity
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aConstitutive Androstane Receptor
650 0 4 _aCytochrome P-450 Enzyme System
_xmetabolism
650 0 4 _aDNA
_xmetabolism
650 0 4 _aEnvironmental Pollutants
_xtoxicity
650 0 4 _aFluorocarbons
_xtoxicity
650 0 4 _aHepatocytes
_xdrug effects
650 0 4 _aHepatomegaly
_xchemically induced
650 0 4 _aHypertrophy
650 0 4 _aLiver
_xenzymology
650 0 4 _aMale
650 0 4 _aOrgan Size
_xdrug effects
650 0 4 _aPPAR alpha
_xmetabolism
650 0 4 _aPeroxisomes
_xmetabolism
650 0 4 _aPregnane X Receptor
650 0 4 _aRats
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aReceptors, Cytoplasmic and Nuclear
_xmetabolism
650 0 4 _aReceptors, Steroid
_xmetabolism
700 1 _aElcombe, Barbara M
700 1 _aFoster, John R
700 1 _aFarrar, David G
700 1 _aJung, Reinhard
700 1 _aChang, Shu-Ching
700 1 _aKennedy, Gerald L
700 1 _aButenhoff, John L
773 0 _tArchives of toxicology
_gvol. 84
_gno. 10
_gp. 787-98
856 4 0 _uhttps://doi.org/10.1007/s00204-010-0572-2
_zAvailable from publisher's website
999 _c19957789
_d19957789