000			01958 a2200553 4500
005			20250515231609.0
264		0	_c20130529
008			201305s 0 0 eng d
022			_a1543-8392
024	7		_a10.1021/mp100015x _2doi
040			_aNLM _beng _cNLM
100	1		_aBruyère, Arnaud
245	0	0	_aEffect of variations in the amounts of P-glycoprotein (ABCB1), BCRP (ABCG2) and CYP3A4 along the human small intestine on PBPK models for predicting intestinal first pass. _h[electronic resource]
260			_bMolecular pharmaceutics _cOct 2010
300			_a1596-607 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aATP Binding Cassette Transporter, Subfamily B
650	0	4	_aATP Binding Cassette Transporter, Subfamily B, Member 1 _xmetabolism
650	0	4	_aATP Binding Cassette Transporter, Subfamily G, Member 2
650	0	4	_aATP-Binding Cassette Transporters _xmetabolism
650	0	4	_aAdministration, Oral
650	0	4	_aAdult
650	0	4	_aAged
650	0	4	_aAged, 80 and over
650	0	4	_aBiological Availability
650	0	4	_aCytochrome P-450 CYP3A _xmetabolism
650	0	4	_aHumans
650	0	4	_aIntestinal Absorption
650	0	4	_aIntestine, Small _xmetabolism
650	0	4	_aMicrosomes _xmetabolism
650	0	4	_aMiddle Aged
650	0	4	_aModels, Biological
650	0	4	_aNeoplasm Proteins _xmetabolism
650	0	4	_aPharmacokinetics
650	0	4	_aTissue Distribution
700	1		_aDeclèves, Xavier
700	1		_aBouzom, Francois
700	1		_aBall, Kathryn
700	1		_aMarques, Catie
700	1		_aTreton, Xavier
700	1		_aPocard, Marc
700	1		_aValleur, Patrice
700	1		_aBouhnik, Yoram
700	1		_aPanis, Yves
700	1		_aScherrmann, Jean-Michel
700	1		_aMouly, Stephane
773	0		_tMolecular pharmaceutics _gvol. 7 _gno. 5 _gp. 1596-607
856	4	0	_uhttps://doi.org/10.1021/mp100015x _zAvailable from publisher's website
999			_c19951016 _d19951016