000 02177 a2200625 4500
005 20250515230747.0
264 0 _c20100721
008 201007s 0 0 eng d
022 _a1476-4687
024 7 _a10.1038/nature09128
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aAlvarez, Sergio E
245 0 0 _aSphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2.
_h[electronic resource]
260 _bNature
_cJun 2010
300 _a1084-8 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aBiocatalysis
650 0 4 _aCell Line
650 0 4 _aEnzyme Activation
650 0 4 _aHumans
650 0 4 _aI-kappa B Kinase
_xmetabolism
650 0 4 _aI-kappa B Proteins
_xmetabolism
650 0 4 _aLysine
_xmetabolism
650 0 4 _aLysophospholipids
_xbiosynthesis
650 0 4 _aMice
650 0 4 _aModels, Molecular
650 0 4 _aNF-KappaB Inhibitor alpha
650 0 4 _aNF-kappa B
_xmetabolism
650 0 4 _aPhosphorylation
650 0 4 _aPhosphotransferases (Alcohol Group Acceptor)
_xgenetics
650 0 4 _aProtein Binding
650 0 4 _aProtein Structure, Tertiary
650 0 4 _aReceptor-Interacting Protein Serine-Threonine Kinases
_xmetabolism
650 0 4 _aSphingosine
_xanalogs & derivatives
650 0 4 _aSubstrate Specificity
650 0 4 _aTNF Receptor-Associated Factor 2
_xchemistry
650 0 4 _aTumor Necrosis Factor-alpha
_xpharmacology
650 0 4 _aUbiquitin-Conjugating Enzymes
_xmetabolism
650 0 4 _aUbiquitin-Protein Ligases
_xmetabolism
650 0 4 _aUbiquitination
_xdrug effects
700 1 _aHarikumar, Kuzhuvelil B
700 1 _aHait, Nitai C
700 1 _aAllegood, Jeremy
700 1 _aStrub, Graham M
700 1 _aKim, Eugene Y
700 1 _aMaceyka, Michael
700 1 _aJiang, Hualiang
700 1 _aLuo, Cheng
700 1 _aKordula, Tomasz
700 1 _aMilstien, Sheldon
700 1 _aSpiegel, Sarah
773 0 _tNature
_gvol. 465
_gno. 7301
_gp. 1084-8
856 4 0 _uhttps://doi.org/10.1038/nature09128
_zAvailable from publisher's website
999 _c19925204
_d19925204