000 02380 a2200709 4500
005 20250515224154.0
264 0 _c20101004
008 201010s 0 0 eng d
022 _a1872-7980
024 7 _a10.1016/j.canlet.2010.04.020
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aTian, Hong-Lei
245 0 0 _aA novel compound modified from tanshinone inhibits tumor growth in vivo via activation of the intrinsic apoptotic pathway.
_h[electronic resource]
260 _bCancer letters
_cNov 2010
300 _a18-30 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAbietanes
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents, Phytogenic
_xchemical synthesis
650 0 4 _aAntioxidants
_xpharmacology
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aCaspase 3
_xmetabolism
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aCytochromes c
_xmetabolism
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDoxorubicin
_xpharmacology
650 0 4 _aFemale
650 0 4 _aHL-60 Cells
650 0 4 _aHeLa Cells
650 0 4 _aHep G2 Cells
650 0 4 _aHumans
650 0 4 _aInhibitory Concentration 50
650 0 4 _aMice
650 0 4 _aMice, Inbred BALB C
650 0 4 _aMice, Nude
650 0 4 _aMitochondria
_xdrug effects
650 0 4 _aNeoplasms
_xdrug therapy
650 0 4 _aPaclitaxel
_xpharmacology
650 0 4 _aPhenanthrenes
_xchemical synthesis
650 0 4 _aPropyl Gallate
_xpharmacology
650 0 4 _aProtein Transport
650 0 4 _aProto-Oncogene Proteins c-bcl-2
_xgenetics
650 0 4 _aReactive Oxygen Species
_xmetabolism
650 0 4 _aReceptor, ErbB-2
_xmetabolism
650 0 4 _aSolubility
650 0 4 _aTime Factors
650 0 4 _aTransfection
650 0 4 _aTumor Burden
_xdrug effects
650 0 4 _aXenograft Model Antitumor Assays
650 0 4 _abcl-2-Associated X Protein
_xmetabolism
700 1 _aYu, Ting
700 1 _aXu, Nai-Ning
700 1 _aFeng, Chao
700 1 _aZhou, Li-Ying
700 1 _aLuo, Hou-Wei
700 1 _aChang, Donald C
700 1 _aLe, Xiao-Feng
700 1 _aLuo, Kathy Qian
773 0 _tCancer letters
_gvol. 297
_gno. 1
_gp. 18-30
856 4 0 _uhttps://doi.org/10.1016/j.canlet.2010.04.020
_zAvailable from publisher's website
999 _c19847581
_d19847581