| 000 | 01702 a2200445 4500 | ||
|---|---|---|---|
| 005 | 20250515223056.0 | ||
| 264 | 0 | _c20100629 | |
| 008 | 201006s 0 0 eng d | ||
| 022 | _a1091-6490 | ||
| 024 | 7 |
_a10.1073/pnas.1004676107 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aTong, Youren | |
| 245 | 0 | 0 |
_aLoss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of alpha-synuclein, and apoptotic cell death in aged mice. _h[electronic resource] |
| 260 |
_bProceedings of the National Academy of Sciences of the United States of America _cMay 2010 |
||
| 300 |
_a9879-84 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAging |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 | _aApoptosis |
| 650 | 0 | 4 | _aAutophagy |
| 650 | 0 | 4 |
_aDopamine _xmetabolism |
| 650 | 0 | 4 | _aHomeostasis |
| 650 | 0 | 4 |
_aKidney Diseases _xgenetics |
| 650 | 0 | 4 | _aLeucine-Rich Repeat Serine-Threonine Protein Kinase-2 |
| 650 | 0 | 4 |
_aLysosomes _xmetabolism |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 | _aMice, Knockout |
| 650 | 0 | 4 | _aOxidation-Reduction |
| 650 | 0 | 4 |
_aProtein Serine-Threonine Kinases _xdeficiency |
| 650 | 0 | 4 | _aUbiquitination |
| 650 | 0 | 4 |
_aalpha-Synuclein _xmetabolism |
| 700 | 1 | _aYamaguchi, Hiroo | |
| 700 | 1 | _aGiaime, Emilie | |
| 700 | 1 | _aBoyle, Scott | |
| 700 | 1 | _aKopan, Raphael | |
| 700 | 1 | _aKelleher, Raymond J | |
| 700 | 1 | _aShen, Jie | |
| 773 | 0 |
_tProceedings of the National Academy of Sciences of the United States of America _gvol. 107 _gno. 21 _gp. 9879-84 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1073/pnas.1004676107 _zAvailable from publisher's website |
| 999 |
_c19812945 _d19812945 |
||