000 01949 a2200493 4500
005 20250515223051.0
264 0 _c20100820
008 201008s 0 0 eng d
022 _a1538-8514
024 7 _a10.1158/1535-7163.MCT-09-1169
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aNing, Yanxia
245 0 0 _aIFNgamma restores breast cancer sensitivity to fulvestrant by regulating STAT1, IFN regulatory factor 1, NF-kappaB, BCL2 family members, and signaling to caspase-dependent apoptosis.
_h[electronic resource]
260 _bMolecular cancer therapeutics
_cMay 2010
300 _a1274-85 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aBreast Neoplasms
_xdrug therapy
650 0 4 _aCarcinoma
_xdrug therapy
650 0 4 _aCaspases
_xmetabolism
650 0 4 _aDrug Evaluation, Preclinical
650 0 4 _aDrug Resistance, Neoplasm
_xdrug effects
650 0 4 _aDrug Synergism
650 0 4 _aEstradiol
_xanalogs & derivatives
650 0 4 _aFemale
650 0 4 _aFulvestrant
650 0 4 _aGene Expression Regulation, Neoplastic
_xdrug effects
650 0 4 _aHumans
650 0 4 _aInterferon Regulatory Factor-1
_xgenetics
650 0 4 _aInterferon-gamma
_xpharmacology
650 0 4 _aNF-kappa B
_xgenetics
650 0 4 _aProto-Oncogene Proteins c-bcl-2
_xgenetics
650 0 4 _aSTAT1 Transcription Factor
_xgenetics
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aTumor Cells, Cultured
700 1 _aRiggins, Rebecca B
700 1 _aMulla, Jennifer E
700 1 _aChung, Haniee
700 1 _aZwart, Alan
700 1 _aClarke, Robert
773 0 _tMolecular cancer therapeutics
_gvol. 9
_gno. 5
_gp. 1274-85
856 4 0 _uhttps://doi.org/10.1158/1535-7163.MCT-09-1169
_zAvailable from publisher's website
999 _c19812677
_d19812677