000 02097 a2200613 4500
005 20250515221356.0
264 0 _c20100824
008 201008s 0 0 eng d
022 _a1528-0020
024 7 _a10.1182/blood-2010-01-261628
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLong, Jianting
245 0 0 _aMultiple distinct molecular mechanisms influence sensitivity and resistance to MDM2 inhibitors in adult acute myelogenous leukemia.
_h[electronic resource]
260 _bBlood
_cJul 2010
300 _a71-80 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAcute Disease
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aAged, 80 and over
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aCell Cycle Proteins
650 0 4 _aCell Line, Tumor
650 0 4 _aCells, Cultured
650 0 4 _aDrug Resistance, Neoplasm
_xdrug effects
650 0 4 _aFemale
650 0 4 _aFlow Cytometry
650 0 4 _aHumans
650 0 4 _aImidazoles
_xpharmacology
650 0 4 _aImmunoblotting
650 0 4 _aIndoles
_xpharmacology
650 0 4 _aLeukemia, Myeloid
_xgenetics
650 0 4 _aMale
650 0 4 _aMiddle Aged
650 0 4 _aNuclear Proteins
_xgenetics
650 0 4 _aPiperazines
_xpharmacology
650 0 4 _aProto-Oncogene Proteins
_xgenetics
650 0 4 _aProto-Oncogene Proteins c-mdm2
_xantagonists & inhibitors
650 0 4 _aReverse Transcriptase Polymerase Chain Reaction
650 0 4 _aSpiro Compounds
_xpharmacology
650 0 4 _aTumor Cells, Cultured
650 0 4 _aTumor Suppressor Protein p53
_xgenetics
650 0 4 _aYoung Adult
650 0 4 _afms-Like Tyrosine Kinase 3
_xgenetics
700 1 _aParkin, Brian
700 1 _aOuillette, Peter
700 1 _aBixby, Dale
700 1 _aShedden, Kerby
700 1 _aErba, Harry
700 1 _aWang, Shaomeng
700 1 _aMalek, Sami N
773 0 _tBlood
_gvol. 116
_gno. 1
_gp. 71-80
856 4 0 _uhttps://doi.org/10.1182/blood-2010-01-261628
_zAvailable from publisher's website
999 _c19762167
_d19762167