| 000 | 01651 a2200469 4500 | ||
|---|---|---|---|
| 005 | 20250515210149.0 | ||
| 264 | 0 | _c20100930 | |
| 008 | 201009s 0 0 eng d | ||
| 022 | _a1932-6203 | ||
| 024 | 7 |
_a10.1371/journal.pone.0009195 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aWalsh, Ann W | |
| 245 | 0 | 0 |
_aMechanistic characterization and molecular modeling of hepatitis B virus polymerase resistance to entecavir. _h[electronic resource] |
| 260 |
_bPloS one _cFeb 2010 |
||
| 300 |
_ae9195 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAmino Acid Sequence |
| 650 | 0 | 4 | _aAmino Acid Substitution |
| 650 | 0 | 4 |
_aAntiviral Agents _xpharmacology |
| 650 | 0 | 4 |
_aBinding Sites _xgenetics |
| 650 | 0 | 4 |
_aDrug Resistance, Viral _xgenetics |
| 650 | 0 | 4 |
_aGuanine _xanalogs & derivatives |
| 650 | 0 | 4 |
_aGuanosine Triphosphate _xchemistry |
| 650 | 0 | 4 | _aHep G2 Cells |
| 650 | 0 | 4 |
_aHepatitis B virus _xenzymology |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aHydrogen Bonding |
| 650 | 0 | 4 | _aKinetics |
| 650 | 0 | 4 |
_aLamivudine _xpharmacology |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 | _aProtein Binding |
| 650 | 0 | 4 | _aProtein Structure, Tertiary |
| 650 | 0 | 4 |
_aRNA-Directed DNA Polymerase _xchemistry |
| 650 | 0 | 4 | _aSubstrate Specificity |
| 650 | 0 | 4 |
_aViral Proteins _xchemistry |
| 650 | 0 | 4 |
_aVirus Replication _xdrug effects |
| 700 | 1 | _aLangley, David R | |
| 700 | 1 | _aColonno, Richard J | |
| 700 | 1 | _aTenney, Daniel J | |
| 773 | 0 |
_tPloS one _gvol. 5 _gno. 2 _gp. e9195 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1371/journal.pone.0009195 _zAvailable from publisher's website |
| 999 |
_c19538597 _d19538597 |
||