| 000 | 01890 a2200529 4500 | ||
|---|---|---|---|
| 005 | 20250515205508.0 | ||
| 264 | 0 | _c20100401 | |
| 008 | 201004s 0 0 eng d | ||
| 022 | _a1520-4804 | ||
| 024 | 7 |
_a10.1021/jm901509a _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aNourry, Arnaud | |
| 245 | 0 | 0 |
_aBRAF inhibitors based on an imidazo[4,5]pyridin-2-one scaffold and a meta substituted middle ring. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _cMar 2010 |
||
| 300 |
_a1964-78 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 |
_aAntineoplastic Agents _xchemical synthesis |
| 650 | 0 | 4 | _aCell Line, Tumor |
| 650 | 0 | 4 |
_aCell Proliferation _xdrug effects |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aImidazoles _xchemical synthesis |
| 650 | 0 | 4 | _aInhibitory Concentration 50 |
| 650 | 0 | 4 | _aMagnetic Resonance Spectroscopy |
| 650 | 0 | 4 | _aMass Spectrometry |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 |
_aPhosphorylation _xdrug effects |
| 650 | 0 | 4 |
_aProtein Kinase Inhibitors _xchemical synthesis |
| 650 | 0 | 4 |
_aProto-Oncogene Proteins B-raf _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aPyridones _xchemical synthesis |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 700 | 1 | _aZambon, Alfonso | |
| 700 | 1 | _aDavies, Lawrence | |
| 700 | 1 | _aNiculescu-Duvaz, Ion | |
| 700 | 1 | _aDijkstra, Harmen P | |
| 700 | 1 | _aMénard, Delphine | |
| 700 | 1 | _aGaulon, Catherine | |
| 700 | 1 | _aNiculescu-Duvaz, Dan | |
| 700 | 1 | _aSuijkerbuijk, Bart M J M | |
| 700 | 1 | _aFriedlos, Frank | |
| 700 | 1 | _aManne, Helen A | |
| 700 | 1 | _aKirk, Ruth | |
| 700 | 1 | _aWhittaker, Steven | |
| 700 | 1 | _aMarais, Richard | |
| 700 | 1 | _aSpringer, Caroline J | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 53 _gno. 5 _gp. 1964-78 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm901509a _zAvailable from publisher's website |
| 999 |
_c19519182 _d19519182 |
||