000 02251 a2200601 4500
005 20250515205406.0
264 0 _c20100407
008 201004s 0 0 eng d
022 _a1538-7445
024 7 _a10.1158/0008-5472.CAN-09-3367
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aZander, Serge A L
245 0 0 _aSensitivity and acquired resistance of BRCA1;p53-deficient mouse mammary tumors to the topoisomerase I inhibitor topotecan.
_h[electronic resource]
260 _bCancer research
_cFeb 2010
300 _a1700-10 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aATP Binding Cassette Transporter, Subfamily B
650 0 4 _aATP Binding Cassette Transporter, Subfamily B, Member 1
650 0 4 _aATP Binding Cassette Transporter, Subfamily G, Member 2
650 0 4 _aATP-Binding Cassette Transporters
_xgenetics
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xadministration & dosage
650 0 4 _aCarcinoma
_xdrug therapy
650 0 4 _aDoxorubicin
_xtherapeutic use
650 0 4 _aDrug Evaluation, Preclinical
650 0 4 _aDrug Resistance, Neoplasm
_xgenetics
650 0 4 _aEnzyme Inhibitors
_xadministration & dosage
650 0 4 _aFemale
650 0 4 _aGene Expression Regulation, Neoplastic
_xdrug effects
650 0 4 _aGenes, BRCA1
_xphysiology
650 0 4 _aGenes, p53
_xphysiology
650 0 4 _aMammary Neoplasms, Animal
_xdrug therapy
650 0 4 _aMaximum Tolerated Dose
650 0 4 _aMice
650 0 4 _aMice, Knockout
650 0 4 _aPhthalazines
_xpharmacology
650 0 4 _aPiperazines
_xpharmacology
650 0 4 _aTopoisomerase I Inhibitors
650 0 4 _aTopotecan
_xadministration & dosage
700 1 _aKersbergen, Ariena
700 1 _avan der Burg, Eline
700 1 _ade Water, Niels
700 1 _avan Tellingen, Olaf
700 1 _aGunnarsdottir, Sjöfn
700 1 _aJaspers, Janneke E
700 1 _aPajic, Marina
700 1 _aNygren, Anders O H
700 1 _aJonkers, Jos
700 1 _aBorst, Piet
700 1 _aRottenberg, Sven
773 0 _tCancer research
_gvol. 70
_gno. 4
_gp. 1700-10
856 4 0 _uhttps://doi.org/10.1158/0008-5472.CAN-09-3367
_zAvailable from publisher's website
999 _c19516007
_d19516007