000			02218 a2200601 4500
005			20250515205313.0
264		0	_c20100526
008			201005s 0 0 eng d
022			_a1754-8411
024	7		_a10.1242/dmm.004440 _2doi
040			_aNLM _beng _cNLM
100	1		_aContreras, Cristina M
245	0	0	_aLkb1 inactivation is sufficient to drive endometrial cancers that are aggressive yet highly responsive to mTOR inhibitor monotherapy. _h[electronic resource]
260			_bDisease models & mechanisms _c
300			_a181-93 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650	0	4	_aAMP-Activated Protein Kinases
650	0	4	_aAnimals
650	0	4	_aCell Line, Tumor
650	0	4	_aCloning, Molecular
650	0	4	_aCornified Envelope Proline-Rich Proteins _xgenetics
650	0	4	_aDisease Models, Animal
650	0	4	_aDrug Screening Assays, Antitumor
650	0	4	_aEndometrial Neoplasms _xdrug therapy
650	0	4	_aEndometrium _xdrug effects
650	0	4	_aEnzyme Activation _xdrug effects
650	0	4	_aEpithelium _xdrug effects
650	0	4	_aFemale
650	0	4	_aIntegrases _xmetabolism
650	0	4	_aIntracellular Signaling Peptides and Proteins _xantagonists & inhibitors
650	0	4	_aMice
650	0	4	_aMice, Transgenic
650	0	4	_aNeoplasm Invasiveness
650	0	4	_aOrgan Specificity _xdrug effects
650	0	4	_aPenetrance
650	0	4	_aProtein Kinase Inhibitors _xpharmacology
650	0	4	_aProtein Serine-Threonine Kinases _xantagonists & inhibitors
650	0	4	_aResponse Elements _xgenetics
650	0	4	_aSirolimus _xpharmacology
650	0	4	_aTOR Serine-Threonine Kinases
700	1		_aAkbay, Esra A
700	1		_aGallardo, Teresa D
700	1		_aHaynie, J Marshall
700	1		_aSharma, Sreenath
700	1		_aTagao, Osamu
700	1		_aBardeesy, Nabeel
700	1		_aTakahashi, Masaya
700	1		_aSettleman, Jeff
700	1		_aWong, Kwok-Kin
700	1		_aCastrillon, Diego H
773	0		_tDisease models & mechanisms _gvol. 3 _gno. 3-4 _gp. 181-93
856	4	0	_uhttps://doi.org/10.1242/dmm.004440 _zAvailable from publisher's website
999			_c19513309 _d19513309