000 02245 a2200589 4500
005 20250515203623.0
264 0 _c20100527
008 201005s 0 0 eng d
022 _a1559-7016
024 7 _a10.1038/jcbfm.2009.272
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aIzuhara, Yuko
245 0 0 _aA novel inhibitor of plasminogen activator inhibitor-1 provides antithrombotic benefits devoid of bleeding effect in nonhuman primates.
_h[electronic resource]
260 _bJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
_cMay 2010
300 _a904-12 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _a4-Aminobenzoic Acid
_xchemical synthesis
650 0 4 _aAnimals
650 0 4 _aDisease Models, Animal
650 0 4 _aDrug Design
650 0 4 _aFemale
650 0 4 _aFibrinolytic Agents
_xchemical synthesis
650 0 4 _aHemorrhage
_xdrug therapy
650 0 4 _aHumans
650 0 4 _aMacaca fascicularis
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Structure
650 0 4 _aPiperazines
_xchemical synthesis
650 0 4 _aPlasminogen Activator Inhibitor 1
_xchemistry
650 0 4 _aProtein Conformation
650 0 4 _aRats
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aRats, Wistar
650 0 4 _aSerine Proteinase Inhibitors
_xchemistry
650 0 4 _aStructure-Activity Relationship
650 0 4 _aThrombosis
_xdrug therapy
650 0 4 _aTiclopidine
_xpharmacology
650 0 4 _aTissue Plasminogen Activator
_xtherapeutic use
650 0 4 _apara-Aminobenzoates
700 1 _aYamaoka, Nagahisa
700 1 _aKodama, Hidehiko
700 1 _aDan, Takashi
700 1 _aTakizawa, Shunya
700 1 _aHirayama, Noriaki
700 1 _aMeguro, Kanji
700 1 _avan Ypersele de Strihou, Charles
700 1 _aMiyata, Toshio
773 0 _tJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
_gvol. 30
_gno. 5
_gp. 904-12
856 4 0 _uhttps://doi.org/10.1038/jcbfm.2009.272
_zAvailable from publisher's website
999 _c19464290
_d19464290