| 000 | 01488 a2200373 4500 | ||
|---|---|---|---|
| 005 | 20250515203418.0 | ||
| 264 | 0 | _c20100312 | |
| 008 | 201003s 0 0 eng d | ||
| 022 | _a1091-6490 | ||
| 024 | 7 |
_a10.1073/pnas.0914163107 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aBoehr, David D | |
| 245 | 0 | 0 |
_aMillisecond timescale fluctuations in dihydrofolate reductase are exquisitely sensitive to the bound ligands. _h[electronic resource] |
| 260 |
_bProceedings of the National Academy of Sciences of the United States of America _cJan 2010 |
||
| 300 |
_a1373-8 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 |
_aEscherichia coli _xenzymology |
| 650 | 0 | 4 | _aLigands |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 |
_aNADP _xchemistry |
| 650 | 0 | 4 | _aNuclear Magnetic Resonance, Biomolecular |
| 650 | 0 | 4 | _aProtein Binding |
| 650 | 0 | 4 | _aProtein Structure, Tertiary |
| 650 | 0 | 4 | _aSubstrate Specificity |
| 650 | 0 | 4 |
_aTetrahydrofolate Dehydrogenase _xchemistry |
| 650 | 0 | 4 |
_aTetrahydrofolates _xgenetics |
| 650 | 0 | 4 | _aThermodynamics |
| 650 | 0 | 4 | _aTime Factors |
| 700 | 1 | _aMcElheny, Dan | |
| 700 | 1 | _aDyson, H Jane | |
| 700 | 1 | _aWright, Peter E | |
| 773 | 0 |
_tProceedings of the National Academy of Sciences of the United States of America _gvol. 107 _gno. 4 _gp. 1373-8 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1073/pnas.0914163107 _zAvailable from publisher's website |
| 999 |
_c19457922 _d19457922 |
||